肺痿冲剂方治疗肺肾两虚,气虚血瘀型特发性肺纤维化临床观察  

Clinical Observation on Feiwei Medicinal Instant Granules in Treating Idiopathic Pulmonary Fibrosis with Syndromes of Lung-kidney Deficiency & Qi Deficiency with Blood Stasis

作　　者：疏欣杨[1] 韩春生[1] 杨道文[1] 于洋[2] 张亚男[2] 张纾难[1] 

机构地区：[1]中日友好医院中医呼吸科,北京100029 [2]北京中医药大学,北京100029

出　　处：《世界中医药》2014年第8期983-986,共4页World Chinese Medicine

基　　金：国家中医药管理局中医药行业科研专项(编号:200807046)

摘　　要：目的:观察肺痿冲剂方治疗特发性肺纤维化肺肾两虚,气虚血瘀证患者的临床疗效。方法:将40例患者随机分为2组,治疗组以肺痿冲剂方治疗,对照组予口服金水宝胶囊,观察2组患者临床疗效、中医单项症状积分、肺功能、HRCT评分、圣乔治生活质量问卷以及6分钟步行试验。结果:在中医单项症状疗效积分(活动后气促、疲倦乏力)、肺功能中一氧化碳弥散量、蜂窝网评分及6分钟步行试验等方面,治疗组改善情况优于对照组,6个月、3个月疗程比较上述趋势更明显。结论:肺痿冲剂方治疗特发性肺纤维化肺肾两虚,气虚血瘀证,在改善临床症状、改善肺弥散功能、延缓蜂窝肺进展、改善生活质量及活动耐力等方面有较显著疗效。Objective：To investigate the clinical effect of Feiwei medicinal instant graneles on patients with idiopathic pulmonary with syndromes of lung-kidney deficiency ＆amp;qi deficiency with blood stasis.Methods：Forty patients were randomly divided into the treatment group given the treatment of Feiwei medicinal instant granuels and control group given the treatment of Jinshuibao capsule.Some out-comes were observed in 2 groups including the CRP score,the TCM individual symptome integration,the 1 ung function,HRCT findings scores,the St.George 1 ife quality questionnaire and the6-min walk test.Results：Compared with patients in the control group,patients in the treatment group had better improvement in terms of the CRP score,cumulative points of efficacy for individual Chinese medicine symptoms（Shortness of breath after activities,fatigue）,DLCO in the function,honeycombing scores,St.George life quality questionnaire and the six-min walk test.Moreover,on the sixth month,most of those outcomes were better than those of the third month.Conclusion：Feiwei medicinal instant granuels treating idiopathic pulmonary fibrosis patients with syndromes of lung-kidney deficiency＆amp;qi deficiency with blood stasis has a significant effect in improving clinical symptoms,life qualities and increasing activity tolerance.

关 键 词：肺痿冲剂方 特发性肺纤维化 肺肾两虚 气虚血瘀 

分 类 号：R256.1[医药卫生—中医内科学]