产科应用舒芬太尼复合左旋布比卡因的镇痛效果  

Analgesic effect of the application of Sufentanil combined with Levobupivacaine in obstetrical department

作　　者：朱国文[1] 

机构地区：[1]浙江省瑞安市人民医院麻醉科,浙江瑞安325200

出　　处：《中国医药导报》2014年第22期80-83,共4页China Medical Herald

基　　金：浙江省瑞安市科技计划项目(编号201204013)

摘　　要：目的：探讨产科应用舒芬太尼复合左旋布比卡因进行麻醉的临床效果。方法收集2011年6月-2013年6月于瑞安市人民医院收治的行剖宫产孕妇118例，随机分为研究组和对照组，每组各59例。对照组给予生理盐水＋0.5%左旋布比卡因麻醉，研究组在对照组基础上予以舒芬太尼，比较两组的麻醉起效时间、镇痛效果、不良反应等项目。结果①两组最高感觉阻滞平面、运动阻滞起效时间、Bromage评分差异无统计学意义（P〉0.05）；研究组达到最高阻滞平面时间[（8.5±1.9）min]、达最大运动阻滞时间[（3.7±1.3）min]短于对照组[（9.8±1.8）、（5.0±1.1）min]，感觉阻滞恢复时间[（273.8±28.0）min]、运动阻滞完全恢复时间[（237.6±26.9）min]长于对照组[（247.1±27.6）、（218.3±27.5）min]，差异均有高度统计学意义（〈0.01）。②研究组镇痛分级比例优于对照组，差异有统计学意义（P〈0.05）。③研究组低血压发生率[3.4豫（2/59）]低于对照组[16.9豫（10/59）]，差异有统计学意义（P〈0.05）；皮肤瘙痒、心动过缓、恶心呕吐等并发症发生率两组差异无统计学意义（P〉0.05）。两组新生儿出生后1、5 min的Apgar评分差异无统计学意义（P〉0.05）。结论产科应用舒芬太尼复合左旋布比卡因具有起效快、镇痛效果明显的特点，值得临床推广。Objective To analyze the analgesic effect of Sufentanil combined with Levobupivacaine in obstetrical de-partment. Methods 118 pregnant woman with cesarean delivery, from June 2011 to June 2013 in the People＇s Hospital of Rui＇an City, were selected and divided into research group and control group randomly, with 59 cases in each group. The control group were given with normal saline＋0.5% Levobupivacaine, the research group were given with Sufentanil on the basses of research group. The anesthesia work time, analgesic effect, untoward effect were compared between the two groups. Results ①The differences of the highest sensory blockade plane, motion block work time, Bromage scores between the two groups was not statistically significant （P〉0.05）. The achievement time of the highest block plane, the achievement time of biggest sports block in research group [（8.5±1.9）, （3.7±1.3） min] were all shorter than those in con-trol group [（9.8±1.8）, （5.0±1.1） min], the sensory blockade recovery time, motion block completely recovery time in re-search group [（273.8±28.0）, （237.6±26.9） min] were all longer than those in control group [（247.1±27.6）, （218.3±27.5） min], the differences were statistically significant （P〈 0.01）. ②The analgesia grade in research group was better than those in control group, the differences were statistically significant （P〈 0.05）. ③The incidence of hypotension in re-search group [3.4% （2/59）] was lower than that in control group [16.9% （10/59）], the difference was statistically signifi-cant （P〈 0.05）; the difference of incidence of cutaneous pruritus, bradycardia, nausea and vomiting between the two groups was not statistically significant （P〉0.05）. The differences of the Apgar scores of the newborn 1, 5 min after the birth between the two groups was not statistically significant （P〉0.05）. Conclusion The application of Sufentanil com-bined with Levobupivacaine in obstetrical department has rapid onset, obv

关 键 词：妇产科 舒芬太尼 左旋布比卡因 麻醉效果 

分 类 号：R614[医药卫生—麻醉学]