Occurrence and Development of Spontaneous Firings in the Telencephalon Neurons of Hynobius leechii  

东北小鲵端脑发生和发育的电生理学特性研究（英文）

作　　者：郑妍[1] 王丽文[1,2] 李丽妍[3] 孙敏[1] 梁传成[1,2] 

机构地区：[1]沈阳师范大学化学与生命科学学院,辽宁沈阳110034 [2]辽宁省教育厅生物系统进化与农业生态重点实验室,辽宁沈阳110034 [3]黄河科技学院医学院,河南郑州450063

出　　处：《Agricultural Science & Technology》2014年第8期1359-1363,共5页农业科学与技术（英文版）

基　　金：Supported by a grant from the Education Department of Liaoning Province(2011196)~~

摘　　要：This study aimed to probe into occurrence and development of spontaneous firings in the telencephalon neurons of Hynobius leechi . [Method] Mi-croelectrode technique was used to record extracellular spontaneous electrical activi-ties of the telencephalon neurons of H. leechi in occurrence and development. [Re-sult] There were three discharge types in the occurrence of telencephalon in H. leechi , with single spontaneous firing and consecutive single spontaneous firing being main-ly apparent. And among the five types in the development of telencephalon, the main discharge type was single spontaneous firing. Along with the occurrence and development of telencephalon, the extracellular discharge intensity enhanced gradual-ly, the discharge duration increased, and the spontaneous firing frequency accelerat-ed, al of which reached the maximum in the adult phase. Fol owing the process of occurrence and development, other discharge types appeared successively. [Conclu-sion] Along with the occurrence and development of the telencephalon in H. leechi , the neuronal excitability increases step by step and the neuronal electrical activities diversify gradual y.[目的]探讨东北小鲵(Hynobius leechii)端脑发生与发育的电生理学特性。[方法]应用微电极电生理技术,对东北小鲵端脑发生和发育不同时期的自发电活动进行在体胞外记录。[结果]东北小鲵端脑发生和发育各时期自发放电形式共有单个放电、连续单个放电、簇状放电、连续簇状放电和不规则放电五种形式。端脑的发生阶段为3种,以单个放电和连续单个放电为主,记录到少数簇状放电;端脑的发育阶段为5种,以单个放电为主。随着端脑发生和发育的进行,胞外放电幅度逐渐提高,放电持续时间增加,放电频率加快,并于成体期达到最大;单个放电时程逐渐缩短;其它放电形式伴随发生发育过程相继出现。[结论]随着东北小鲵端脑发生与发育,神经元的兴奋性逐步提高,神经元电活动形式逐渐多样化。

关 键 词：Hynobius leechi TELENCEPHALON OCCURRENCE DEVELOPMENT Sponta-neous firings 

分 类 号：Q424[生物学—神经生物学]