药品规格与其临床单次给药剂量的一致性及适配性调查分析  

Survey on the consistency and suitability between drug specifications and its clinical single doses

作　　者：徐梦丹[1] 巫丽娟[2] 

机构地区：[1]广东药学院药科学院,广州510006 [2]广州医科大学附属第四医院,广州511447

出　　处：《中国当代医药》2014年第24期7-12,共6页China Modern Medicine

基　　金：广东省教育厅育苗工程项目(2012WYM-0083)

摘　　要：目的基于临床处方用药信息数据,考察药品规格与其临床单次给药剂量的一致性及适配性状况,为医疗机构选择药品规格、制药企业设计药品规格、政府部门制订有关药品规格管理政策等提供实证参考。方法从广州医科大学附属第四医院的医院信息系统中随机抽取10 d的处方信息数据,排除部分不符合要求的用药记录后,以5533张处方、16 357条用药记录及621个药品品规作为研究样本,并建立用药记录数据库,然后对药品规格与其临床单次给药剂量一致性及适配性的用药记录频次与所占比例等统计指标进行分析。结果在全部用药记录中,药品规格与其临床单次给药剂量之间不一致、与不适配的用药记录比率分别为38.6%和20.3%。结论目前中国市面上流通的药品,尤其是儿科药品,其规格在与临床单次给药剂量的适配性方面还有较大的提升空间,政府部门、药品生产企业、医院等相关机构应共同努力解决好这一问题。Objective To provide the empirical references for medical institutions selecting drug specifications,pharma-ceutical enterprises designing drug specifications,and government departments formulating relevant drug specifications management policies through surveying the consistency and suitability between drug specifications and its clinical sin-gle doses based on the clinical prescription information data. Methods The prescription information data of 10 days were randomly selected from the hospital information system of the Fourth Affiliated Hospital of Guangzhou Medical University,after excluding some drug-using records which did not conform to the requirements,the 5533 prescriptions, 16 357 drug-using records and 621 drugs were treated as the research sample,and a database was established,then the statistical indicators such as the frequencies and percentages of drug-using records of consistency and suitability be-tween drug specifications and its clinical single doses were analyzed. Results The inconsistency rate and unsuitability rate between drug specifications and its clinical single doses of total drug-using records were 38.6% and 20.3%,re-spectively. Conclusion As for the drugs,especially the pediatric drugs currently circulating on the market in our coun-try,the suitability between their specifications and clinical single doses has a large improvement space.The related orga-nizations,such as government departments,pharmaceutical enterprises,hospitals and so on,should make joint efforts to solve the problem.

关 键 词：药品规格 临床单次给药剂量 一致性 适配性 药物剂型 

分 类 号：R95[医药卫生—药学]