4，4’-双(二乙氧基膦酰甲基)联苯合成工艺研究  

Study on synthesis of 4,4-bis( diethylphosphonomethyl)-diphenyl

作　　者：郭鹏涛[1] 张海娟[1] 张存社[1] 沈寒晰[1] 郑阿龙 

机构地区：[1]陕西省石油化工研究设计院,陕西省石油精细化学品重点实验室,陕西西安710054

出　　处：《应用化工》2014年第8期1435-1436,共2页Applied Chemical Industry

基　　金：陕西省科技厅项目(2012K08-13)

摘　　要：以联苯二氯苄和亚磷酸三乙酯为原料,合成4,4’-双(二乙氧基膦酰甲基)联苯。研究了配料摩尔比、反应时间、反应温度、析出溶剂用量对收率的影响。结果表明,最佳合成工艺条件为:配料亚磷酸三乙酯和联苯二氯苄的摩尔比3.5∶1,反应温度为160℃,反应时间为5 h,析出溶剂用量140 mL。在此条件下,收率可达97.4%,产品含量达98.2%。In order to biphenyl two benzyl chloride and phosphate ester as raw material in the synthesis of three,4,4’-bis（ diethylphosphonomethyl）-diphenyl. Effect of the mixing molar ratio,reaction time,reac-tion temperature,dosage of solvent precipitation on the yield were investigated . The results indicated that the optimum conditions of the synthesis process：blending ratio 3 . 5：1 ,reaction temperature 160 ℃,reac-tion time is 5 h,the precipitation solvent dosage is 140 mL under this condition,the yield is up to 97 . 4%,the content of the product 98 . 2%.

关 键 词：4  4’-双(二乙氧基膦酰甲基)联苯 合成 亚磷酸三乙酯 

分 类 号：TQ241.3[化学工程—有机化工]