893例体检女性生殖道感染与宫颈病变的临床分析  

Clinical Analysis of 893 Cases of Female Reproductive Tract Infection and Cervical Lesions

作　　者：杨妹[1] 吴孝杰[1] 庞正钰 林怡[1] 陈彦明[1] 徐文瑜[1] 

机构地区：[1]湛江市妇幼保健院,广东湛江524038

出　　处：《中国初级卫生保健》2014年第8期51-52,共2页Chinese Primary Health Care

摘　　要：目的分析女性宫颈病变状况,探讨宫颈癌及癌前病变与生殖道感染的相关性及危险因素,为早期检测、预防和治疗提供临床依据。方法对2012年1—6月在我院健康体检的893例妇女采用液基薄层细胞学检测(TCT),进行宫颈癌筛查。对初筛阳性病例进一步检测人乳头瘤病毒(HPV)感染情况,对检测结果进行统计、分析。结果宫颈病变程度与HPV感染呈正相关(x^2=20.87,P<0.01),宫颈病变程度和HPV感染率城乡女性之间无显著性差异,TCT检测结果和HPV阳性率无明显区别(P>0.05)。结论流行病学和分子生物学资料表明,HPV感染能够引起宫颈上皮内瘤变(CIN)及子宫颈癌的发生,因此,定期对40~60岁宫颈病变高发感染期进行细胞学和病毒检测,采取相应的干预、治疗措施,才能更有效地早期发现和阻断宫颈病变的发展。OBJECTIVE To analyze pathological status of female cervical, cervical cancer and precancerous lesions and genital tract infection and risk factors for early detection, prevention, and treatment of clinical evidence. METHODS In 893 women examined by thinprep liquid based cytology test（TCT）, cervical cancer screening from January to June in 2012 in target hospital. The screening positive cases were further detection of human papilloma virus（HPV） infection, statistics, analysis of the test results. RESULTS The degree of cervical disease and HPV infection is related to process（X~=20.87, P〈0.01）, and cervical lesions and viral infection rate has no obvious difference, cervicitis or not, for clinical screening of cervical lesions of little significance, there was no obvious dif- ference between the positive rate of TCT and HPV（P〉0.05）. CONCLUSION Epidemiology and molecular biology data shows that, human papilloma virus（HPV） infection can cause cervical intraepithelial neoplasia（CIN） and cervical cancer, the key lies in 40 - 60 years old of cervical lesions were detected in the infection period of cytology and virus, take appropriate intervention, treatment, could be more effective early detection and blocking the development of lesions.

关 键 词：宫颈癌 生殖道感染 宫颈病变 

分 类 号：R711.3[医药卫生—妇产科学]