离子液体作为助溶剂制备L-天冬酰胺分子印迹聚合物  

Preparation of L-Asparagine molecularly imprinted polymer usinionic liuid as cosolvent

作　　者：张向荣[1] 胡小玲[1] 管萍[1] 李季[1] 杨龙飞[1] 赵娜[1] 

机构地区：[1]西北工业大学理学院化学系,空间应用物理与化学教育部重点实验室,西安710129

出　　处：《功能材料》2014年第14期14052-14056,共5页Journal of Functional Materials

基　　金：国家自然科学基金资助项目(21174111);西北工业大学研究生创业种子基金资助项目(Z2013145)

摘　　要：以水-乙腈为溶剂、离子液体[Bmim]Br作为助溶剂,L-天冬酰胺(L-Asn)为模板分子,4-乙烯基吡啶为功能单体,乙二醇二甲基丙烯酸酯为交联剂,使用沉淀聚合法制备得到分子印迹聚合物L-Asn-MIPs-IL。采用SEM对其形貌进行了表征,并研究了[Bmim]Br在印迹聚合物制备中的作用以及L-Asn-MIPs-IL对L-Asn的吸附识别性能。结果表明,与用水-乙腈作溶剂制备的L-Asn-MIPs相比,L-Asn-MIPs-IL具有粒径小、产率高、比表面积大、吸附量高(饱和吸附量为15.49mg/g)、吸附速率快(160min达到吸附平衡)、识别性能强(L-Asn与L-精氨酸L-Arg之间的分离因子为1.68)和对映体拆分性能优良(相对于D-Asn)的优点。The molecularly imprinted polymers （L-Asn-MIPs-IL）were firstly prepared by precipitation polymer-ization using 4-vinylpyridine（4-VP）as functional monomers and ethylene glycol dimethyl acrylate（EGDMA）as cross-linker in the presence of L-Asparagine as template molecule in aqueous-acetonitrile and 1-butyl-3-methy-limidazolium bromide [Bmim]Br solution.The scanning electron microscopy （SEM）exhibited that the L-Asn-MIPs-IL were small particles with narrow particle size distributions.Compared with that of the molecularly im-printed polymers （L-Asn-MIPs）synthesized in aqueous-acetonitrile solution without [Bmim]Br,the yield and specific surface area of L-Asn-MIPs-IL was significantly higher.The results showed that L-Asn-MIPs-IL for L-Asn possessed higher saturation adsorption amount,faster adsorption speed,better selective adsorption capaci-ty and finer separation property for the enantiomers of Asparagine compared to L-Asn-MIPs.The equilibrium adsorption amount in 100 mg/L L-Asn solution was 15.49 mg/g,the adsorption equilibrium can be reached within 160 min and the separation factor between L-Asn and L-Arg was 1.68.

关 键 词：分子印迹聚合物 L-天冬酰胺 离子液体 沉淀聚合法 吸附 

分 类 号：TQ317[化学工程—高聚物工业]