持续胰岛素泵治疗结直肠癌合并2型糖尿病围手术期疗效观察  

Efficacy of insulin pump therapy of colorectal cancer complicated with type 2 diabetes mellitus in peri-operation period

作　　者：王雷雷 朱绥 周小爱 钮雁文[4] 

机构地区：[1]宁波市鄞州区第三医院内科,浙江宁波315191 [2]宁波市鄞州区姜山中心卫生院,浙江宁波315100 [3]宁波市鄞州第二医院内分泌科,浙江宁波315100 [4]宁波市第一医院内分泌科,浙江宁波315100

出　　处：《中国现代医生》2014年第25期122-124,127,共4页China Modern Doctor

基　　金：浙江省卫生厅成果转化及推广项目(2013XZB05)

摘　　要：目的观察结直肠癌合并2型糖尿病围手术期采用持续皮下胰岛素泵输注(CSII)控制血糖的临床疗效。方法选择60例拟行手术治疗的结直肠癌合并2型糖尿病患者,随机分为治疗组和对照组,每组各30例,治疗组采用CSII治疗(CSII组),对照组采用常规多次皮下注射(MSII组)治疗,观察目标血糖达标时间、治疗前后两组血糖值、术中血糖、胰岛素用量、术前准备时间、低血糖发生率、伤口愈合情况、感染发生率住院总时间等临床指标。结果治疗后两组各点血糖水平明显下降,效果满意。治疗后CSII组餐前血糖、早餐后2 h血糖、睡前血糖均较MSII组低,CSII组血糖达标所用时间、胰岛素用量、术前准备时间、住院总时间、伤口愈合情况及感染发生率均低于MSII组,低血糖发生率、术中血糖两组无明显差异。结论 CSII在结直肠癌合并2型糖尿病患者围手术期中的疗效及安全性方面均优于MSII,值得推广。Objective To observe the clinical efficacy of control blood glucose by using CSII for the people who suf-fers？from colorectal cancer complicated with type 2 diabetes mellitus in peri-operation period. Methods Sixty patients who sufferred from colorectal cancer complicated with type 2 diabetes mellitus were selected and were randomly divid-ed into treatment group（30 cases） and control group（30 cases）. The treatment group was treated with CSII （CSII group）, while the control group was treated with conventional subcutaneous injection （MSII group）. The blood glucose level be-fore and after treatment, blood glucose time required to reach the target, the incidence of hypoglycemia, insulin dosage, preoperative preparation time, time of hospitalization,the incidence of wound healing, and infection were detected. Re-sults Blood glucose levels of two groups decreased significantly after treatment, which reached effect satisfaction. The time of blood glucose control, the rate of hypoglycemia, insulin dosage, preoperative preparation time, hospitalization time,wound healing and infection rate of group CSII were lower than those of MSII group. Conclusion Efficacy and safety in peri-operative time of CSII in colorectal cancer operation with type 2 diabetes mellitus is superior to that of MSII.

关 键 词：胰岛素泵 皮下胰岛素注射 结直肠癌合并2型糖尿病 围手术期 

分 类 号：R619[医药卫生—外科学]