SPIO与Gd-DTPA增强MRI对肝占位病变的诊断价值  

SPIO and Gd-DTPA enhanced MRI diagnostic value of the liver lesions

作　　者：范万峰[1] 曹新山[2] 马德晶[2] 张虎[2] 王萍[2] 

机构地区：[1]滨州医学院临床医学院医学影像学教研室,滨州256603 [2]滨州医学院附属医院放射科

出　　处：《滨州医学院学报》2014年第4期280-282,共3页Journal of Binzhou Medical University

基　　金：山东省科技发展计划(2010GSF10265)

摘　　要：目的评价超顺磁性氧化铁(SPIO)与钆动态增强(Gd-DTPA)MRI对肝占位病变的诊断价值。方法回顾性分析30例肝占位病变的SPIO增强及Gd-DTPA动态增强MRI资料。结果 SPIO增强后T2WI良性病灶对应的增强前后肝脏的信号强度(SIL)和肝脏内局限性病变的信号强度(SIM)均较平扫明显降低,而恶性病灶SIL较平扫明显降低,SPIO增强后SIM与平扫差异无统计学意义,病灶与正常肝组织的CNR较平扫明显增加;对于病灶直径≤2.0cm的肝占位病变,SPIO增强扫描检出率高于Gd-DTPA;且SPIO增强扫描的定性诊断率高于Gd-DTPA。结论 SPIO增强MRI可提高肝占位病变的临床诊断率,具有一定的可靠性。Objective To evaluate the value of SPIO and Gd-DTPA enhanced MRI in the diagnosis of liver lesions .Methods Gd-DTPA dynamic enhanced and SPIO-enhanced MRI findings in 30 patients with liver lesions were retrospectively analyzed . Results In SPIO-enhanced MRI ,the signal intensity of normal hepatie parenchyma was decreased in T 2WI while the CNR be-tween lesions and normal liver tissues signifieantly improved .For SPIO-enhanced MRI ,the rate of detection of hepatic lesions （≤2.0 cm）and the accuracy of characteristic diagnosis was higher than that of Gd-DTPA-enhanced MRI .Conclusion SPIO-en-hanced M RI can increase the diagnosis rate of liver lesions .

关 键 词：磁性氧化铁 肝占位 磁共振成像 

分 类 号：R814.4[医药卫生—影像医学与核医学]