不同引产方式用于终止孕12～15周妊娠的临床研究  

The Effectiveness of Different Methods in Termination of 12-15 Weeks of Pregnancy

作　　者：黄金瑞[1] 兰景尤 

机构地区：[1]广西医科大学附属南宁市第一人民医院,广西南宁530000 [2]武鸣县人民医院

出　　处：《中外医学研究》2014年第24期3-5,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的：探讨不同引产方式用于终止12~15周妊娠的临床效果。方法：将170例停经12~15周孕妇需要终止妊娠者随机分为三组。A组60例，米索前列醇联合利凡诺羊膜腔外引产；B组57例，口服米非司酮及阴道放置米索前列醇药物引产；C组53例，利凡诺羊膜腔外引产。结果：A、B组单次引产成功率明显高于C组，清宫率、产后2 h阴道流血量均低于C组，差异有统计学意义（P〈0.05）；A组与B组比较，单次引产成功率、阴道流血量差异无统计学意义（P〉0.05），B组清宫率低于A组，差异有统计学意义（P〈0.05）；三组患者均无明显不良反应。结论：米非司酮联合阴道放置米索前列醇用于终止12~15周妊娠引产成功率高，简单、安全、出血少、副作用少，值得临床推广。Objective：To investigate the clinical effectiveness of different methods in termination of 12-15 weeks of pregnancy.Method：A total of 170 women seeking for terminating 12-15 weeks of gestation were randomly divided into three groups,group A（n=60,Misoprostol combined with extra-amniotic cavity injection of Rivanol）,group B（n=57,Mifepristone combined with vaginal Misoprostol）,group C（n=53,extra-amniotic cavity injection of Rivanol）.The clinical effectiveness of these three methods was evaluated.Result：Compared with group C,higher success rate of labor induction,lower rate of post-abortion curettage, less amount of vaginal bleeding were found in group A and group B（P〈0.05）.Compared with group A,lower rate of post-abortion curettage was observed in group B, there were no significant differences in the success rate of labor induction and amount of vaginal bleeding between group A and group B.There were no significant adverse reactions among three groups.Conclusion：Mifepristone combined with vaginal Misoprostol in termination of 12-15 weeks of pregnancy are high success rate,simple,safe,small side effect,and worthy of widely clinical.

关 键 词：米索前列醇 羊膜腔外引产 依沙丫啶 米非司酮 

分 类 号：R719.3[医药卫生—妇产科学]