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作 者:王迎春[1] 段丽芳[1] 刘玉琴[1] 赖金华[1]
机构地区:[1]北京大学深圳医院药剂科,广东深圳518036
出 处:《中国药房》2014年第34期3186-3188,共3页China Pharmacy
摘 要:目的:了解住院患者麻醉药品的应用情况,为临床合理用药提供参考。方法:采用限定日剂量(DDD)和药物利用指数(DUI)作为评价药物利用的客观指标,对我院2012年8月-2013年7月住院患者使用的麻醉药品进行统计、分析。结果:我院有麻醉药品12种,包括注射剂6种、口服片剂5种、外用贴剂1种。药品金额排前3位的麻醉药品是注射用瑞芬太尼、舒芬太尼注射液、芬太尼透皮贴剂。麻醉药品消耗主要分布在肿瘤内科、微创介入科、麻醉科、普外科、重症监护室等。芬太尼透皮贴剂、可待因片、吗啡缓释片、羟考酮缓释片(40 mg/片)和硫酸吗啡片的DUI>1,其余7种麻醉药品的DUI<1。结论:我院麻醉药品消耗基本用于肿瘤患者及手术麻醉和镇痛中,符合麻醉药品用药管理规定。其中,手术镇痛以舒芬太尼注射液、芬太尼注射液为主,癌痛治疗以羟考酮缓释片、吗啡注射液为主。我院癌性疼痛患者的镇痛用药方向符合世界卫生组织要求,但是消耗量和DUI仍偏小,特别是口服剂型。OBJECTIVE: To probe into the utilization of narcotic drugs in the inpatients so as to provide reference for rational drug use. METHODS: The utilization of narcotic drugs in the inpatients of our hospital during Aug. 2012-Jul, 2013 was analyzed statistically using DDD and DUI as index. RESULTS: 12 kinds of narcotic drugs were used in our hospital, including 6 injections, 5 oral tablets and 1 external patch. Remifentanil for injection, Sufentanil citrate injection and Fentanyl transdermal patch took up the top 3 places in the list of consumption. The narcotic drugs were mainly used in oncology department, minimally-invasive intervention department, department of anesthesiology, department of general surgery and ICU, etc. DUI was less than 1 among these drugs except for Fentanyl transdermal patch, Codeine tablets, Morphine tablets, Oxycodone sulfate sustained-release tablets (40 mg/tablet) and Morphine sulfate tablets. CONCLUSIONS: The narcotic drugs of our hospital are mostly used in cancer patients, operative anesthesia and analgesia. Sufentanil injection and Fentanyl injection were used for surgical anesthesia, and Oxycodone sustained-release tablets and Morphine injection for cancer pain. The utilization of analgesic drugs in cancer pain patients is in line with the re- quirements of WHO, but consumption and DUI of them are in low level, especially for oral form.
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