临床药师对1例婴儿痉挛症患儿术后抗感染治疗的药学监护  

Pharmaceutical Care for Postoperative Anti-infection Treatment in a Case of Infantile Spasms Syndrome by Clinical Pharmacists

作　　者：李楠[1] 党大胜[1] 史国兵[1] 魏学忠[2] 

机构地区：[1]沈阳军区总医院药剂科,沈阳110016 [2]沈阳军区总医院神经外科,沈阳110016

出　　处：《中国药房》2014年第34期3253-3255,共3页China Pharmacy

摘　　要：目的:探讨临床药师在婴儿痉挛症患儿术后抗感染治疗中的作用。方法:临床药师监测与随访1例婴儿痉挛症患儿幕上开颅左侧颞前叶及内侧结构切除术后的抗菌药物应用。患儿脑脊液培养为肺炎克雷伯菌和耐甲氧西林金黄色葡萄球菌感染,并根据该患儿自身情况计算抗菌药物的用量,制订个体化用药方案:先后使用了美罗培南300 mg、tid;哌拉西林/他唑巴坦钠1.8 g、q8h;万古霉素200 mg、tid。结果:患儿颅内感染治愈,且用药期间未发生药物不良反应。结论:临床药师配合医师参与特殊人群临床用药方案制订,有利于确保患者用药的安全、有效。OBJECTIVE： To investigate the role of clinical pharmacists on postoperative anti-infection treatment for patient with infantile spasms syndrome. METHODS： Clinical pharmacist monitored and followed up the utilization of antibiotics in a patient with infantile spasms after left anterior temporal lobectomy and temporosphenoid lobe internal structure resection. Klebsiella pneumoniae and MRSA infection were included in cerebrospinal fluid culture. According to the condition of patient, individual medication scheme was developed, i.g. meropenem 300 rag, tid; piperacillin/tazobactam sodium 1.8 g, q8h; vancomycin 200 mg, tid. RESULTS： The intracranial infection was cured, and no ADR was found during medication. CONCLUSIONS： Clinical pharma- cists cooperated with physicians to develop medication scheme for special group so as to guarantee safe and effective use of drugs.

关 键 词：婴儿痉挛症 抗菌药物 临床药师 药学监护 

分 类 号：R969.3[医药卫生—药理学] R978.1[医药卫生—药学]