家蝇金属硫蛋白的研究进展  

Research advances in metallothionein in Musca domestica

作　　者：赵志刚[1,2] 霍新北[1,2] 王学军[1,2] 康殿民[1] 景晓[1,2] 赖世宏[1] 张世水[1] 曲宝泉[1] 

机构地区：[1]山东大学预防医学研究院,山东省疾病预防控制中心,济南250014 [2]山东省传染病预防控制重点实验室,济南250014

出　　处：《中国媒介生物学及控制杂志》2014年第4期382-384,共3页Chinese Journal of Vector Biology and Control

基　　金：山东省医药卫生科技发展计划项目(2009HW055)~~

摘　　要：金属硫蛋白(MT)是一类广泛存在于生物体内的金属结合蛋白,富含半胱氨酸的小分子蛋白,能螯合多种金属离子,因其功能独特,近年来对MT各方面的研究日益受到重视。该文简述了家蝇MT的结构特点、理化性质和分布情况,以及参与体内解毒、清除自由基和微量元素代谢功能的研究现状及进展。Metallothioneins （MT） are a class of cysteine-rich, low-molecular-weight metal-binding proteins widely distributed in organisms, which can chelate various metal ions. In recent years, MT has been increasingly studied in different aspects due to its special functions. This paper briefly describes the structural characteristics, physical and chemical properties, and distribution ofMT and reviews the research advances in its participation in detoxication, free radical scavenging, and trace element metabolism.

关 键 词：金属硫蛋白 家蝇 功能 研究进展 

分 类 号：R384.2[医药卫生—医学寄生虫学] S481.4[医药卫生—基础医学]