湿毒清胶囊联合依诺沙星预防膀胱壁瓣输尿管成形术术后感染40例  

Clinical Observation on Enoxacin Combined with Shiduqing Capsules for Preventing Infection after Bladder Wall Flap Ureteroplasty on 40 Cases

作　　者：谢淼[1] 沙文[1] 崔庆明[1] 

机构地区：[1]河南省濮阳市油田总医院泌尿外科,河南濮阳457001

出　　处：《中国药业》2014年第16期114-115,共2页China Pharmaceuticals

摘　　要：目的研究依诺沙星联合湿毒清胶囊预防膀胱壁瓣输尿管成形术术后感染的临床疗效。方法随机抽取2010年1月到2013年10月医院收治的输尿管下段损伤患者80例,随机分为对照组和观察组,各40例。所有患者采用经膀胱壁瓣输尿管成形术治疗治疗输尿管下段损伤,对照组患者在术中和术后采用依诺沙星预防感染,观察组患者在术前和术后排气后加用湿毒清胶囊。治疗结束后,观察临床疗效,统计并发症、疼痛以及感染的的发生情况。结果观察组总有效率为92.50%,对照组为90.00%,两组无显著性差异(P>0.05)。观察组共有6例患者在治疗后出现了感染等并发症,对照组共发生15例,两组并发症总发生率有统计学差异(P<0.05);观察组患者各时点疼痛评分均低于对照组,差异有统计学意义(P<0.05);两组患者均未发生严重不良反应。结论膀胱壁瓣输尿管成形术治疗输尿管下段损伤临床疗效好,应用依诺沙星联合湿毒清胶囊的患者感染等术后并发症少,疼痛较轻,值得推广。Objective To study the clinical efficacy of enoxacin combined with Shiduqing Capsules for preventing infection after bladder wall flap ureteroplasty. Methods 80 patients with lower ureteral injury treated in our hospital from January 2010 to October 2013 were randomly selected and randomly divided into the control group and the observation group,40 cases in each group. The lower ureteral injury in all the cases was treated by bladder wall flap ureteroplasty. The control group adopted intraoperative and postoperative enoxacin for preventing infection,while the observation group was added with Shiduqing Capsule before operation and after postoperative anal exhaust. The clinical effects after treatment were observed in the two groups. The occurrence situation of complications, pain and infection injury were investigated and statistically analyzed. Results The total effective rate was 92.50% in the observation group and 90. 00% in the control group without statistically significant difference between the two groups（ P 〉 0.05）;6 cases of postoperative complications such as infection occurred in the observation group and 15 cases in the control group, the total occurrence rate of complications had statistical difference between the two groups（P 〈 0.05）;the pain score at each timepoint in the observation group was lower than that in the control group with statistical difference between them（P 〈 0.05）; no serious adverse reactions occurred in the two groups. Conclusion Bladder wall flap ureteroplasty has better effect for treating lower ureteral injury by bladder wall flap ureteroplasty and the combination of enoxacin and Shiduqing Capsules has few complications and slight pain,which deserves to be generalized.

关 键 词：依诺沙星 湿毒清胶囊 膀胱壁瓣输尿管成形术 输尿管下段损伤 

分 类 号：R285.6[医药卫生—中药学] R286[医药卫生—中医学]