Bland-Altman 分析法评价 GEM Premier 3000血气分析仪与BC-5800血液细胞分析仪检测血红蛋白及血细胞比容的相关性和一致性  

Assessment of Correlation and Concordance of GEM Premier 3000 Blood Gas Analyzer and BC-5800 Blood Cell Analyzer for Detecting Hemoglobin and Hematocrit Assessed by Bland-Altman Method

作　　者：余跃天[1] 朱琤[2] 毛恩强[2] 殷荣[1] 李昱洁[1] 杭燕南[1] 曹建国[1] 

机构地区：[1]上海交通大学医学院附属仁济医院重症监护室,上海200001 [2]上海交通大学医学院附属瑞金医院急诊科,上海200025

出　　处：《医学临床研究》2014年第7期1255-1258,共4页Journal of Clinical Research

基　　金：上海市卫生局青年科研项目（20114y119）

摘　　要：【目的】使用Bland-Altman分析法评价床边血气分析仪检测血红蛋白（Hb）及血细胞比容（HCT ）结果与中心实验室检测结果是否具有相关性及一致性。【方法】对100份动脉血标本分别使用迈瑞BC-5800血液分析仪及GEM Premier 3000血气分析仪行Hb及 HCT检测，并对结果行相关性分析及Bland-Altman分析。【结果】两种方法所测得Hb的相关系数 r ＝0．807，P ＜0．01，回归方程为Y＝24．163＋0．742X ，两组方法所测得 HCT的相关系数 r ＝0．709，P ＜0．01，回归方程为 Y＝8．881＋0．635X ，两组数据均有较好的相关性。但经Bland-Altman法分析，Hb及HCT检测95％的可信区间均在临床可以接受的界限之外，一致性欠佳。【结论】GEM 血气分析仪与BC血液细胞分析仪方法测得指标均有较好的相关性，但一致性欠佳。床边即时检验尚无法完全替代传统检验方法。Objective To assess the correlation and concordance of the results of bedside blood gas analyzer （GEM Premier 3000） and blood cell analyzer （BC-5800） for measuring hemoglobin and hematocrit with the results of central laboratory assessed by Bland-Altman method .[Methods]Hemoglobin and hematocrit of 100 arterial blood samples were measured by Mairui BC-5800 blood analyzer and GEM Premier 3000 analyzer .The results were taken for correlation analysis and Bland-Altman analysis .[Results] The correlation coefficient（r） of hemoglobin measured by two methods was 0 . 807（ P〈0 .01） ,and the regression equation was Y =24 .163＋0 .742X .The correlation coefficient （r） of hematocrit measured by two analyzers was 0 .709（ P〈0 .01） ,and the regression equation was Y=8 .881＋0 .635X .There was good correlation of the data between two methods .Bland-Altman analysis showed that 95% confidence intervals of either hemoglobin or hematocrit were not within clinically acceptable range .The concordance of measurements by two analyzers was unsatisfactory .[Conclusion] There is good correlation of hemoglobin and hematocrit between two methods ,but the concordance is unsatisfactory .Bedside immediate measurement can not completely substitute for conventional measurement .

关 键 词：统计学 医学 血气分析 仪器和设备 血液化学分析 仪器和设备 血红蛋白测定 血细胞比容 

分 类 号：R446.11[医药卫生—诊断学]