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机构地区:[1]中国人民解放军武汉疗养院门诊,湖北武汉430074
出 处:《医学临床研究》2014年第7期1294-1295,1298,共3页Journal of Clinical Research
摘 要:【目的】探讨老年糖尿病(DM )合并代谢综合征(MS)患者动脉僵硬度的变化及影响因素。【方法】选取来本院疗养的246例老年DM患者,以有无合并MS分为MS组( n=120)和无MS组( n=126),另选取62例健康老年人作为对照组。对所有患者进行脉搏波传导速度(PWV ),血压,血脂,空腹血糖(FBG ),高敏C反应蛋白(hs-CRP),空腹胰岛素(FINS),胰岛素抵抗指数(HOMA-IR),腰围,体质量指数(BMI)的检测。【结果】DM 患者组颈--股动脉PWV显著高于对照组( P<0.05),多因素回归分析显示:PWV与FBG ,hs-CRP ,FINS ,血压,血脂,患者年龄,以及 HOMA-IR表现为正相关。【结论】老年DM会使动脉僵硬度显著增大,且随着MS并发呈上升趋势。To explore the changes and influential factors of arterial stiffness in elderly patients with diabetesmellitus (DM) mergedmet abolicsyndrome(MS).[Methods]Totally 246 elderly patients with DM in our sanatorium were chosen .According to the merging or not ,all patients were divided into merging MS group( n=120) and no merging MS group( n=126) .Other 62 healthy old people were chosen as the control group .Pulse wave conduction velocity (PWV) ,blood pressure ,blood lipid ,fasting blood glucose(FBG) ,high-sensitivity C-reactive protein(hs-CRP) ,fasting insulin(FINS) ,insulin resistance index (HOMA IR) ,waist circumference and body mass index(BMI) of all patients were measured .[Results] Neck-femoral artery PWV in DM patients was significantly higher than that in control group(P〈0.05).Multiple-factor regression analysis showed that PWV was positively correlated with FBG ,hs-CRP ,FINS ,blood pressure ,blood lipid ,patients' age and HOMA-IR .[Conclusion]Senile DM can significantly increase arterial stiffness .Arterial stiffness has a rising trend due to the merging MS.
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