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机构地区:[1]辽宁中医药大学附属医院,辽宁沈阳110032
出 处:《辽宁中医药大学学报》2014年第8期141-143,共3页Journal of Liaoning University of Traditional Chinese Medicine
基 金:辽宁省卫生厅课题资助项目(200940)
摘 要:目的:观察止痛散治疗寒湿痹阻型类风湿关节炎的临床疗效和安全性。方法:将144例寒湿痹阻型类风湿关节炎患者随机分为两组,对照组:口服甲氨蝶呤(MTX),第1周5 mg,第2周7.5 mg,第3周起10 mg周1次口服;试验组:在口服MTX基础上采用止痛散穴位贴敷,每5 d 1次,连续3次。观察治疗前、4周、12周后关节晨僵时间、关节压痛数、关节肿胀数、CRP和不良反应情况。结果:试验组在治疗3~4周后临床症状逐渐缓解;对照组在治疗5~6周后临床症状逐渐缓解。试验组治疗4周及12周后在关节晨僵时间、关节压痛数、关节肿胀数、CRP改善方面均优于对照组;试验组ACR20有效率77.61%,对照组56.52%;试验组总有效率89.55%,对照组总有效率72.46%。结论:止痛散穴位贴敷治疗寒湿痹阻型类风湿关节炎安全有效。Objective : To investigate the clinical efficacy and safety of Analgesia Power in the treatment of cold and dampness blockage of rheumatoid arthritis. Methods: 144 cases of cold and dampness blockage of rheumatoid arthritis were randomly divided into two groups. In control group : oral methotrexate ( MTX ), the first week 5 mg, the second week 7.5 rag, 10 mg a week from the third week, orally once. In experimental groups : MTX, the use of oral Analgesia Power aeupoint application, once every 5 days, 3 times in a row. We observed the joint time of morning stiffness, tender joint count, swollen joint count, CRP and adverse reactions before treatment, 4 weeks, 12 weeks after treatment. Results : In the experimental group 3-4 weeks after treatment, clinical symptoms gradually eased. In control group 5-6 weeks after treatment, the clinical symptoms gradually eased. Experimental group's morning stiffness in the joints, joint tenderness, swollen joint count, CRP improvements were better than those of the control group 4 weeks and 12 weeks after treatment. The experimental group's ACR20 efficient was 77.61% and the control group's was 56.52%. The experimental group's total efficiency was 89.55% and in the control group, the total efficiency was 72.46%. Conclusion : Analgesia Power aeupoint sticking therapy is safe and effective for rheumatoid arthritis of cold and dampness blockage.
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