老年人隐匿性自身免疫性糖尿病与2型糖尿病临床特征对比分析  

A contrastive analysis on clinical features of latent autoimmune diabetes in adults and type 2 diabetes mellitus in the elderly

作　　者：梁波[1] 李良毅[1] 林家煜[1] 林如海[1] 蔡辉耀[1] 林夏鸿[1] 李希圣[1] 

机构地区：[1]福建医科大学附属第二医院内分泌科,泉州362000

出　　处：《中华老年医学杂志》2014年第8期877-880,共4页Chinese Journal of Geriatrics

基　　金：福建医科大学附属第二医院苗圃基金（2012MP48）;福建省自然科学基金（2012J01332）

摘　　要：目的 探讨老年人隐匿性自身免疫性糖尿病（LADA）与2型糖尿病（T2DM）临床特征的差异. 方法 对我院确诊的41例老年LADA患者和49例T2DM患者的临床特征进行回顾性的对比分析. 结果 老年LADA组体质指数、空腹及餐后2hC肽水平、三酰甘油、血清白蛋白水平低于T2DM组,而空腹血糖及餐后2h血糖高于T2DM组;两组病程、血压、肝功能和肾小球滤过率比较,差异无统计学意义. 结论 老年LADA患者与T2DM患者比较,血糖相对较高,体质量和三酰甘油水平相对较低,胰岛B细胞功能较差.Objective To explore the differences in clinical features between the latent autoimmune diabetes in adults （LADA） and type 2 diabetes mellitus （T2DM） in the elderly.Methods Clinical features of 41 cases with LADA and 49 cases with T2DM were retrospectively analyzed and compared.Results （1） Body mass index （BMI）,fasting and postprandial levels of cpeptide,triglyceride （TG） and serum albumin were lower in LADA patients than in T2DM patients.（2） The levels of fasting and postprandial blood glucose were higher in LADA patients than in T2DM patients.（3） There were no statistically significant differences in the disease course,blood pressure （BP）,and the functions of liver and kidney between LADA and T2DM patients.Conclusions As compared with T2DM patients,LADA patients have higher blood glucose level,lower BMI and TG level,and poorer function of islet B cell.But there is no significant difference in the chronic complications between two groups.

关 键 词：糖尿病 1型 糖尿病 2型 

分 类 号：R587.1[医药卫生—内分泌]