西地那非治疗新生儿持续胎儿循环  

Sildenafil treatment of neonatal continuous fetal circulation

作　　者：彭冬霞 

机构地区：[1]山东省巨野县人民医院小儿科,山东菏泽274900

出　　处：《世界最新医学信息文摘》2014年第14期36-37,共2页World Latest Medicine Information Electronic Version

摘　　要：目的探讨分析西地那非治疗新生儿持续胎儿循环的临床疗效。方法回顾性分析2013年1月至2013年11月间在我院进行治疗的16例新生儿持续胎儿循环患儿的临床记录资料。结果应用3剂量治疗后，患者的总有效率高于应用1剂后的总有效率，具有显著性差异（P 〈0.05）；但应用2剂和应用3剂后的总有效率相比，无显著性差异（P 〉0.05）。和治疗前相比，患者治疗后6h、12h、24h、48h、72h 的 sao2、Pao2均高于对照组，PaMP、Paco2均低于对照组，具有显著性差异（P 〈0.05）。结论西地那非治疗新生儿持续胎儿循环的临床疗效显著，值得临床推广应用。Objective to investigate clinical efficacy of sildenafil in treatment of newborn persistent fetal circulation. Methods clinical records of 32 cases of newborn children with persistent fetal circulation in our hospital from January 2013 to november 2013 were reviewed. Results After treatment, the total effective rate of patients with 3 doses was significant higher than that of patients with 1 doses, （P 〈0.05）; the difference of total effective rate between patients with 2 doses and patients with 3 doses was not significant（P 〉0.05）.compared before treatment , after treatment for 6h, 12h, 24h, 48h, 72h ,the sao2, Pao2 of treatment group were higher , PaMP, Paco2 of treatment group were lower than that of the control group（P 〈0.05）. Conclusion Clinical efficacy of sildenafil in the treatment of neonatal persistent fetal circulation is significant, worthy of clinical application.

关 键 词：西地那非 新生儿 持续胎儿循环 临床效果 

分 类 号：R722.1[医药卫生—儿科]