清肺培元微丸辅助治疗141例艾滋病肺部感染患者的临床观察  

Complementary Treatment of 141 HIV/AIDS Patients with Pulmonary Infection by Qingfei Peiyuan Micro-pill:a Clinical Observation

作　　者：马秀霞[1] 徐立然[1] 郑志攀[1] 孟鹏飞[1] 王东旭 宋夕元[1] 

机构地区：[1]河南中医学院第一附属医院艾滋病临床研究中心,郑州450000 [2]河南省开封市中医院呼吸科,河南475000

出　　处：《中国中西医结合杂志》2014年第8期960-963,共4页Chinese Journal of Integrated Traditional and Western Medicine

基　　金："十一五"国家科技重大专项资助项目(No.2008ZX10005-003G)

摘　　要：目的观察清肺培元微丸对艾滋病肺部感染痰热壅肺证患者的影响。方法将141例艾滋病肺部感染痰热壅肺证患者随机分为治疗组(94例)和对照组(47例),治疗组在西医治疗基础上加用清肺培元微丸,疗程28天。观察两组患者症状、体征改善情况,并检测体温、胸部X线及白细胞。结果在治疗第7、21、28天时治疗组中医证候评分低于对照组,两组比较差异有统计学意义(P<0.05);治疗第7、21、28天时治疗组疗效优于对照组,差异有统计学意义(P<0.05);第7天时治疗组体温低于对照组;治疗前、治疗第7天时两组白细胞正常例数比较,差异无统计学意义(P>0.05),但治疗第14、21、28天时两组比较,差异有统计学意义(P<0.05);治疗前、治疗第7、28天时治疗组胸部X线正常例数与对照组比较,差异无统计学意义(P>0.05);治疗第14、21天时两组比较,差异有统计学意义(P<0.05)。结论清肺培元微丸对艾滋病肺部感染痰热壅肺证患者有一定的辅助治疗效果。Objective To observe the effect of Qingfei Peiyuan Micro-pill （QPM） on HIV/AIDS patients with pulmonary infection of phlegm heat obstructing lung syndrome （PHOLS）. Methods Totally 141 HIV/AIDS patients with pulmonary infection of PHOLS were randomly assigned to the treatment group （94 cases） and the control group （47cases）. On the basis of Western medicine, patients in the treat- ment group took QPM. The therapeutic course for all was 28 days. The improvement of symptoms and signs was observed. The body temperature （BT）, chest X ray, and white blood cells （WBCs） were de- tected. Results The Chinese medical syndrome score was lower in the treatment group than in the con- trol group at the 7th, 21st, and 28th day of treatment, showing statistical difference （P 〈0.05）. The effi- cacy was better in the treatment group than in the control group at the 7th, 21 st, and 28th day of treat- ment, showing statistical difference （P 〈0.05~）. The BT was lower in the treatment group than in the con- trol group on the 7th day. There was no statistical difference in the patient number with normal WBCs on the 7th day （P 〉0.05）. But there was statistical difference in the patient number with normal WBCs on the 14th, 21 st, and 28th day of treatment （P 〈0.05）. There was no statistical difference in the patient number with normal chest X ray on the 7th and 28th day of treatment （P 〉0.05）. But there was statistical difference in the patient number with normal chest X ray on the 14th and 21 st day of treatment （P 〈 0.05）. Conclusion QPM had certain complementary effect on HIV/AIDS patients with pulmonary infection of PHOLS.

关 键 词：艾滋病 肺部感染 痰热壅肺证 清肺培元微丸 

分 类 号：R259[医药卫生—中西医结合]