聚己内酯改性 O-磺化壳聚糖/胆固醇的混合单分子膜性能  

Mixed monolayers of poly (ε-caprolactone) grafting O-sulfonated chitosan with cholesterol

作　　者：毛扬帆[1] 辛梅华[1] 李明春[1] 邢宇[1] 

机构地区：[1]华侨大学材料科学与工程学院环境友好功能材料教育部工程中心,福建厦门361021

出　　处：《功能材料》2014年第15期15031-15035,15040,共6页Journal of Functional Materials

基　　金：科技部科技人员服务企业资助项目(2009GJC40030);福建省重点科技资助项目(2009H0030);福建省自然科学基金资助项目(2011J01312,2012J01396)

摘　　要：制备聚己内酯改性O-磺化壳聚糖(HSCS-gPCL),用FT-IR、EA和1 H NMR对产物进行表征,并研究其与胆固醇的混合单分子膜性质。结果表明,单组份HSCS-g-PCL单分子膜π-A曲线为膨胀型,而混合单分子膜则转变为凝聚型并均具有明显LE-LC相转变;随着胆固醇含量的增加,混合单分子膜的崩溃压和极限分子面积降低,最大压缩模量增大;胆固醇摩尔分数为0.6时两组份分子间作用力从相互排斥转为相互吸引,为0.8时,体系超额自由能ΔGexc最小,两组份间相容性最好,体系最稳定。O-sulfonated chitosan-graft-poly（ε-caprolactone）（HSCS-g-PCL）was synthesiz- ed and the structure of it was characterized by FT-IR,1 H NMR and EA.The properties of mixed monolayers of HSCS-g-PCL and cho-lesterol were studied.Experimental results indicated that when cholesterol was added,the π-A isotherms of the HSCS-g-PCL monolayer turned from expand type into condensation type and had obvious LE-LC phase transi-tion.As the cholesterol molar ratio increased,collapse pressure and the limiting molecular area of mixed mono-layers decreased,meanwhile maximum compression modulus increased.The value of Δ exc changed from an re-pulsive interaction to an attractive interaction between HSCS-g-PCL and cholesterol with a critical point when cholesterol molar ration was 0.6.When molar ratio of cholesterol was 0.8,Δ exc of mixed monolayers was mini-mum and the mixed monolayer was the most stable.

关 键 词：壳聚糖 磺化 聚己内酯 胆固醇 单分子膜 

分 类 号：O636.1[理学—高分子化学]