早产儿肺透明膜病发病及预后的高危因素分析  

Analysis on the high risk factors of pathogenesis and prognosis with hyaline membrane disease in premature infant

作　　者：朱良梅[1] 李晓春[1] 孔少云[1] 汪敏慧[1] 

机构地区：[1]安庆市立医院新生儿科,安徽246003

出　　处：《安徽卫生职业技术学院学报》2014年第4期45-46,共2页Journal of Anhui Health Vocational & Technical College

摘　　要：目的:探讨早产儿肺透明膜病(HMD)发病及影响预后的高危因素,为新生儿肺透明膜病发病提供预防措施。方法:选择67例HMD患儿为研究对象,同期住院的1194例早产儿为对照组,回顾性分析与HMD发病及预后有关的危险因素。结果:围生期窒息、前置胎盘、胎盘早剥、小胎龄、低体重为早产儿HMD发生的高危因素,而胎膜早破及产前使用糖皮质激素对HMD有预防作用。而胎龄越小、体重越低HMD预后越差,早期使用肺表面活性物质明显提高HMD存活率。结论:对孕母特别是高危妊娠孕母重视产前检查,及时发现问题并予以正确处理,减少早产,积极消除HMD高危因素,积极治疗,降低HMD的发病率及病死率。Objective： To discuss the high risk factors of pathogenesis and prognosis with hyaline membrane disease in premature infant, and to provide preventive measures for hyaline membrane disease in premature infant. Methods： 67 children who were confirmed hyaline membrane disease were chosen as the objects of the research, as the same time in the hospital, l194 premature infants were allocated into control groups, the high risk factors of pathogenesis and prognosis with HMD would be retrospective analysis. Results： Asphyxia in perinatal period, placenta previa, placental abruption, small gestational age, low-body weight was the high risk factors of the happening of HMD, but premature rupture of membranes and antenatal glucocorticoids were preventions for HMD. The smaller of the gestational age and the lower of the weight, the prognosis of HMD were the worse. In the early stage, using the pulmonary surfactants could improve the survival rates of HMD. Conclusion： Pregnant woman, especially high risk pregnant women should attach importance to prenatal examination, find problems in time and correctly dispose, eliminate the high risk factors of HMD, reduce the premature infants, treat actively, and reduce the morbidities and the case fatality rates of HMD.

关 键 词：早产儿 肺透明膜病 高危因素 预后 

分 类 号：R722.6[医药卫生—儿科]