甲亢合并周期性麻痹26例临床诊治体会  

Clinical experience on diagnosis and treatment of 26 patients with hyperthyroidism complicated by periodic paralysis

作　　者：姜甲军 

机构地区：[1]丹东市慢性病研究所甲状腺科,辽宁118000

出　　处：《中国临床新医学》2014年第8期732-734,共3页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

摘　　要：目的探讨甲亢合并周期性麻痹的临床特点,减少漏诊、误诊的发生。方法回顾性分析26例甲亢合并周期性麻痹患者的临床资料。结果患者经补钾后1-18 h病情迅速缓解,并予正规抗甲状腺药物治疗后22例甲功恢复正常,2例反复发作2次,经调整抗甲状腺药物后甲功恢复正常,2例因口服药出现不良反应改^131I治疗甲功恢复正常。26例随访6个月-1年内无周期性麻痹复发。结论甲亢合并周期性麻痹补钾治疗后症状迅速改善,积极有效控制甲亢是预防复发的关键,同时注意避免饱餐、感染、过度劳累、静脉输入高渗葡萄糖等诱发因素。Objective To investigate the clinical featurs of hyperthyroidism patients with periodic paralysis in order to dearease the rate of missed diagnosis and misdiagnosis. Methods A retrospective analysis of the clinical data was performed of 26 patients with hyperthyroidism complicated by periodic paralysis. Results Within 1to 18 h after potassium treatment,the patients＇ symptoms and signs quickly relieved,and after antithyroid drug treatment thyroid function returned to normal in 22 patients. Two patients experienced 2 times of recurrent attacks and their thyroid function returned to normal after adjusting antithyroid drug. Due to adverse reaction of oral drugs,2 patients were treated with^131 I treatment instead of oral drugs and their thyroid function returned to normal after^131 I treatment. Within 6to 12 months of follow-up,no recurrence of periodic paralysis appeared in 26 patients. Conclusion For patients with hyperthyroidism complicated by periodic paralysis,potassium supplementation can rapidly improve their symptoms;active and effective antithyroid drugs treatment is key to preventing recurrence; at the same time,it is necessary to avoid the predisposing factors such as overeat ingestion,infection,excessive exertion,and intravenous infusion of hypertonic glucose and so on,in order to prevent recurrence.

关 键 词：甲亢 周期性麻痹 体会 

分 类 号：R582[医药卫生—内分泌]