丹栀逍遥散加味治疗脑卒中后抑郁临床研究  

Clinical Observation of Flavored Danzhi Xiaoyaosan in the Treatment of Post-stroke Depression

作　　者：左刚[1] 张霞[2] 

机构地区：[1]河南中医学院第三附属医院,河南郑州450008 [2]河南中医学院第一附属医院,河南郑州450000

出　　处：《中医学报》2014年第9期1367-1368,共2页Acta Chinese Medicine

基　　金：郑州市科技攻关项目(编号:112PPTSF319-6)

摘　　要：目的:观察丹栀逍遥散加味治疗脑卒中后抑郁症的临床疗效。方法:收集脑卒中后抑郁症患者80例,随机分为两组。试验组40例,用丹栀逍遥散加味治疗;对照组40例,单纯用盐酸氟哌噻吨片(黛立新)治疗。结果:试验组有效率与对照组比较差异无统计学意义(P>0.05),但是在第8周试验组患者HAMD评分明显低于对照组,两组比较差异有统计学意义(P<0.05)。另外,试验组与对照组的不良反应方面比较,差异有统计学意义(P<0.05)。结论:丹栀逍遥散治疗脑卒中后抑郁症具有疗效好,不良反应少的特点。Objective：To observe the clinical efficacy of flavored Danzhi Xiaoyaosan in the treatment of post-stroke depression. Methods： 80 cases with post-stroke depression were randomly divided into test group and control group ,40 cases in each group. The test group was given flavored Danzhi Xiaoyaosan treatment. The control group was given simply Flupentixol（ Dai Lixin） treatment. Compared the clinical efficiency of two group, there was no significant difference （ P 〉 0.05 ）. But in the 8-week trial, the HAMD score of test group was significantly lower than that of control group. The difference was statistically significant （ P 〈 0.05 ）. In addition, compared the adverse effects of the two groups, the difference was statistically significant （P 〈 0.05 ）. Conclusion ：Danzhi Xiaoyaosan in the treatment of poststroke depression has good efficacy with minor adverse reactions.

关 键 词：脑卒中后抑郁症 丹栀逍遥散 盐酸氟哌噻吨片 

分 类 号：R277.749.4[医药卫生—中医学]