2013年六盘水市健康人群乙型肝炎表面抗体水平监测  

Monitoring on the Antibody Level of Hepatitis B Surface Antigen Among the Healthy Population,Liupanshui City,2013

作　　者：田兴国[1] 褚彪[1] 朱仁珍 任艳[1] 金宣华[1] 林江丽[1] 刘勇[1] 

机构地区：[1]六盘水市疾病预防控制中心,贵州六盘水553001

出　　处：《预防医学论坛》2014年第8期596-597,600,共3页Preventive Medicine Tribune

摘　　要：目的了解六盘水市健康人群乙型肝炎(乙肝)表面抗体水平,评价疫苗接种效果和人群免疫状况,为制定乙肝免疫规划提供依据。方法采用分层随机抽样和简单随机抽样的方法抽取健康人群血样。采用酶联免疫吸附(ELISA)法进行乙肝表面抗体检测。结果检测2区县459份血样,抗-HBs阳性率66.01%。抗-HBs阳性率随年龄增高而降低(P<0.01),有乙肝疫苗接种史人群的抗-HBs阳性率高于无接种史人群(P<0.05)。结论六盘水市将乙肝疫苗纳入免疫规划后,人群免疫水平明显提高。Objective To understand the antibody level of the hepatitis B surface antigen among the healthy population in Liupanshui city,evaluate the vaccination effect and the immune status,so as to provide scientific basis for working out strategies for hepatitis B prevention and control. Methods Serum samples of healthy people were selected with stratified random sampling and simple random sampling method.The antibody was detected by enzyme-linked immunosorbent assay（ELISA）. Results A total of 459 serum samples were detected in 2districts（counties）and the average positive rate of the antibody was 66.01%.The positive rate of HBsAb was dropping along with increasing ages in the healthy population（P〈0.01）.The positive rate of HBsAb in the healthy population with hepatitis B vaccination was higher than whose without vaccination（P〈0.05）. Conclusion The antibody level of the hepatitis B surface antigen is significantly rising among the healthy population in Liupanshui city,since the hepatitis B vaccination is brought into EPI.

关 键 词：健康人群 乙型肝炎 表面抗体 监测 

分 类 号：R512.62[医药卫生—内科学]