新疆维吾尔自治区学龄前儿童麻疹抗体水平分析  

Measles antibody levels among preschool children in Xinjiang Uygur Autonomous Region

作　　者：关静[1] 玛合木提江.库尔班 甫尔哈提.吾守尔 尹遵栋[2] 沙吾拉西[1] 

机构地区：[1]新疆维吾尔自治区疾病预防控制中心,乌鲁木齐830011 [2]中国疾病预防控制中心免疫规划中心

出　　处：《中国学校卫生》2014年第7期1033-1035,共3页Chinese Journal of School Health

摘　　要：目的评价新疆维吾尔自治区学龄前儿童麻疹抗体水平,为有针对性地开展麻疹科学防治提供参考依据。方法在新疆维吾尔自治区的12个县（市）,采集1-6岁学龄前儿童静脉血2 105人份,采用酶联免疫吸附试验（ELISA）法检测麻疹免疫球蛋白（IgG）抗体。结果学龄前儿童麻疹IgG抗体总阳性率为93.11%,几何平均滴度（GMT）为1∶2 055.62。2岁后随着年龄的增长,GMT呈下降趋势。各地麻疹抗体阳性率和GMT较不平衡,局部仍有麻疹暴发的可能。结论对大龄儿童及青少年进行麻疹疫苗的强化免疫,提高免疫水平,是进一步控制麻疹暴发和流行的有效措施。Objective To evaluate measles antibody levels among preschool children in Xinjiang Uygur Autonomous Re- gion land to develop scientific prevention and cure of measles. Methods Twelve counties have been randomIy selected. Totally 2 105 blood samples of preschool children in group of 1-6 years were taken and the measles IgG antibody deteeted by ELISA. Resuits The total positive rate of measles antibody was 93.11% and the measles antibody GMT was 1 ： 2 055.62. GMT showed a deerease trend after 2 years with the age increasing. Measles antibody positive rate and measles antibody GMT were unbalanced between different regions,which suggest the possibility of measles outbreak in some areas. Conclusion Measles vaccine strengthening immunization of older children and teenagers is the better way to control the outbreak or epidemic of measles.

关 键 词：儿童 学龄前 麻疹 抗体 维吾尔族 

分 类 号：R195[医药卫生—卫生统计学] R511.1[医药卫生—卫生事业管理]