室间隔封堵器在成人细小动脉导管未闭介入治疗中的疗效和安全性  

Application of VSD occluders in small patent ductus arteriosus with interventional therapy

作　　者：高虹[1] 张智伟[2] 冯程[1] 陈立新[1] 梁海南[1] 李军[1] 叶钜亨[1] 

机构地区：[1]暨南大学第二临床医学院心内科,广东深圳518020 [2]广东省人民医院心血管病研究所

出　　处：《临床心血管病杂志》2014年第8期712-715,共4页Journal of Clinical Cardiology

摘　　要：目的：探讨细小型成年动脉导管未闭（PDA）患者的造影、介入治疗特点,观察应用室间隔缺损（VSD）封堵器关闭此类动脉导管未闭的疗效、安全性和意义。方法：选择成年PDA患者25例,造影观察PDA的形态、大小,将其分为长管型10例（A组）,迂曲不规则型9例（B组）,动脉瘤型6例（C组）。UCG显示直径1.2～2.8mm,造影显示最小直径1.2mm,最大直径4.3mm。PDA长度7.9～11.9mm,平均（9.9±1.3）mm。结果：选择对称型室间隔封堵器和肌部室间隔封堵器进行介入封堵治疗,治疗前后肺动脉压力无明显差异,但造影与TTE测量最窄处直径差异有统计学意义（P〈0.05）。总体成功率100%。随访无明显降主动脉缩窄、左肺动脉狭窄及其他并发症。结论：室间隔封堵器关闭细小型PDA疗效肯定、安全。Objective：To study the effect of interventional therapy with the VSD occluders in small patent ductus arteriosus （PDA）. Method： All 25 small PDA patients included tlong tube （A group, n= 10）, circuitous irreg- ular tube （B group, n= 9）, aneurysm type （C group, n = 6）. Implantation of symmetrical interventrical septum occluders and muscular interventrical septum occluders were carried out in these patients. The diameter of the PDA was messured by X-ray and the pressure of pulmonary artery change was documented. Result：Technical suc- cess was obtained in all patients. There were not obvious changes of the pressure of pulmonary artery between preoperation and postopration, but the diameter of PDA detected by trans-thoracic echocardiography （UCG） was significant different with X-ray（P〈0.05）,and the shape could not be revealed correctly by UCG. All ducts were closed completely. All showed excellent clinical improvement in the follow up without obstruction to the left pul- monary artery and SBE did not occure. Conclusion.. For the adult small PDA patients, complete closure using the symmetrical muscular or membranous VSD occluder is safe and effective.

关 键 词：动脉导管未闭 封堵器 经导管关闭 成人 

分 类 号：R541.1[医药卫生—心血管疾病]