浸润注射局麻药联合口服NSAIDs对TKA术后疼痛的疗效观察  

The efficacy of infiltrating injection of local anesthetic and oral NSAIDs for postoperative pain of total knee arthroplasty

作　　者：梁大宝 桂斌捷[1] 

机构地区：[1]安徽医科大学第一附属医院骨科,合肥230022

出　　处：《安徽医科大学学报》2014年第9期1348-1350,共3页Acta Universitatis Medicinalis Anhui

基　　金：安徽高校省级自然科学基金(编号:KJ2012A172)

摘　　要：观察浸润注射局麻药联合口服非甾体抗炎药(NSAIDs)治疗全膝关节置换(TKA)术后疼痛的疗效。50例行TKA患者随机分为2组。研究组术中膝关节浸润注射罗哌卡因加围手术期口服塞来昔布;对照组应用静脉镇痛泵。研究组术后3 d的VAS评分(4.2±0.6,4.6±0.8,4.6±1.1)较对照组(6.5±0.7,6.4±1.0,6.1±0.9)低,差异有统计学意义(P<0.05);研究组吗啡补救量(10.6±7.7)mg较对照组(18.4±10.3)mg少,差异有统计学意义(P<0.05)。浸润注射罗哌卡因联合口服塞来昔布可有效缓解TKA术后疼痛,优于静脉镇痛泵。Abstract To observe the efficacy of infiltrating injection of local anesthetic and oral NSAIDs for postoperative pain of total knee arthroplasty （TKA）. 50 patients undergoing TKA were randomly assigned to two groups. The study group received intraoperative infiltrating injection of ropivacaine around knee and perioperative oral celecoxib. The control group received intravenous analgesia pump. The VAS scores in postoperative 3 days of the study group （4.2 ± 0.6,4.6 ±0. 8,4. 6 ±1.1 ） were lower than the control group （6.5 ±0. 7,6. 4± 1.0,6. 1±0. 9）. The differ- ence was statistically significant（ P 〈 0.05 ）, and the dose of remedial morphine of the study group （ 10. 6±7.7 ）mg was less than the control group （ 18.4 ±10. 3 ） rag. The difference was statistically significant（ P 〈 0. 05 ）. Infiltra- ting injection of ropivacaine and oral celecoxib could effectively relieve postoperative pain of TKA which was better than intravenous analgesia pump.

关 键 词：全膝关节置换 局部浸润 塞来昔布 

分 类 号：R687.4[医药卫生—骨科学]