融合酶构建技术在酶的改性以及多功能酶的构建方面的应用  

The Application of Fusion Enzyme on Chracter Modification and the Constructing of Multiple-functional enzyme

作　　者：鄢凯舟 陆兵[1] 梁钰婷[1] 张云开[1] 陈桂光[1] 梁智群[1] 

机构地区：[1]广西大学生命科学与技术学院,南宁530004

出　　处：《中国生物工程杂志》2014年第7期69-75,共7页China Biotechnology

摘　　要：融合酶技术是酶的改造技术之一。应用融合酶技术还可以创造出多功能的新酶,这些新酶有望应用于食品、化工等领域。目前研究表明,融合酶在低聚糖制备,生物燃料,生物材料,氨基酸发酵以及生物传感器等领域极具应用前景。融合酶的构建技术有理性设计和非理性设计,这两种技术各有利弊。整理了近年融合酶在以上领域中的研究成果,对融合酶的工业应用进行讨论。Fusion enzyme is one of the strategies to modify the characteristic of enzymes. Multiple-functional enzymes may be constructed by enzyme fusion. To our knowledge,fusion enzymes were applied in the production of oligosaccharide,biofuel,biomaterial,amino acid and biosensor. Fusion enzyme can be formed by rational design and non-rational design. Each stratagy has the advantage that the other don＇t. According to the application of these two strategies be used in rescent years,we illustrated the application of fusion enzyme in industry.

关 键 词：融合酶 改性 多功能酶 

分 类 号：Q814[生物学—生物工程]