晚期血吸虫病住院患者焦虑抑郁与生活质量状况及影响因素研究  

Investigation on anxiety, depression and life quality of hospitalized patients with advanced schistosomiasis and related influencing factors

作　　者：潘洁[1] 周瑞红[1] 刘科丰[1] 肖水源[2] 邵志伟[1] 来如意[1] 余慧琼[1] 罗志红[3] 

机构地区：[1]湖南省血吸虫病防治所附属湘岳医院/血吸虫病重点专科,湖南岳阳414000 [2]中南大学公共卫生学院,湖南长沙410078 [3]湖南省血吸虫病防治所,湖南岳阳414000

出　　处：《热带医学杂志》2014年第8期1082-1085,1092,共5页Journal of Tropical Medicine

基　　金：湖南省科技厅科研项目(2011SK3190)

摘　　要：目的调查晚期血吸虫病住院患者焦虑、抑郁与生活质量状况,并探讨焦虑、抑郁发生的影响因素。方法应用焦虑自评量表(SAS)、抑郁自评量表(SDS)和世界卫生组织生存质量测定量表简表(WHOQOL-BREF)对206例晚期血吸虫病患者焦虑、抑郁情绪和生活质量情况进行问卷调查。采用SPSS17.0建立数据库,进行统计描述并采用逐步回归法分析影响患者焦虑、抑郁发生的因素。结果 206例晚期血吸虫病患者焦虑发生率为70.4%、抑郁发生率为69.4%、焦虑合并抑郁发生率为58.3%。晚期血吸虫病患者焦虑、抑郁得分显著高于国内常模(P<0.005),生活质量各领域得分低于常模(P<0.05),焦虑、抑郁与生活质量各维度呈负相关(P<0.005)。多元逐步回归分析显示,晚期血吸虫病分型、文化程度是影响焦虑情绪的主要因素。文化程度、住院次数、晚期血吸虫病手术史是影响抑郁情绪的主要因素,其中文化程度高、有晚期血吸虫病手术史为焦虑、抑郁情绪的保护因素。结论晚期血吸虫病住院患者普遍存在焦虑、抑郁负性情绪,且生活质量低,受多方面因素的影响,临床应予以重视,并及时采取有效的干预措施。Objective To explore anxiety, depression and life quality of hospitalized patients with advanced schistosomiasis and its influencing factors, so as to provide theoretical basis for administering clinical psychological interventions.Methods Self-rating Anxiety Scale（SAS）, Self- Rating Depression Scale（SDS）, and The WHOQOL-BREF Form were used to survey the anxiety, depression and life quality of 206 hospitalized patients with advanced schistosomiasis by mean of questionnaires. The data was analyzed by SPSS 17.0 software with descriptive statistics and multiple stepwise regression analysis.Results The incidence of anxiety, depression among 206 advanced schistosomiasis patients reached 70.4% and 69.4%,respectively. The incidence rate of having both anxiety and depression was 58.3%. SAS and SDS scores of advanced schistosomiasis were significantly higher than those of the national norm（P〈0.005）; the WHOQOL-BREF scores was lower than that of the national norm（P0.05）. The anxiety, depression and quality of life were negatively related（P〈0.005）. Multiple stepwise regression analysis indicated that education level and diagnosis were the risk factors of anxiety; education level,times of hospitalization and history of portal hypertension operation were the risk factors of depression, while high education level and history of portal hypertension operation were considered as the protective factors. Conclusion The incidence of negative emotion in advanced schistosomiasis patients is higher, and life quality is lower than those of the national norm. It is influenced by various factors. We should pay attention to psychological condition and quality of life of the patients and take timely and effective intervention measures.

关 键 词：晚期血吸虫病 焦虑 抑郁 负性情绪 

分 类 号：R532.21[医药卫生—内科学]