线栓法制备大鼠局灶性脑缺血模型手术操作的研究进展  

Advance on the operation of the suture-occuluded method for focal celebral ischemia model in rats

作　　者：石将通 赵忠[1] 蒙息标 田顺亮[2] 

机构地区：[1]广西桂林医学院临床医学院,桂林541001 [2]广西桂林医学院人体解剖学教研室,桂林541004

出　　处：《中国比较医学杂志》2014年第7期68-71,共4页Chinese Journal of Comparative Medicine

基　　金：2013年广西壮族自治区大学生创新创业训练项目804

摘　　要：线栓法大鼠大脑中动脉阻塞模型被普遍认为是标准的大鼠局灶性脑缺血动物模型。该模型在制备过程中,易受到多重因素的影响,其中手术操作对模型的成功制作起着关键作用。文章从大鼠颈部主要动脉的解剖位置、手术切口位置的选择、手术左右侧别的选择,以及插线位置的选择进行了综述。Middle cerebral artery occlusion model with suture-occluded method in rats is widely regarded as the standard animal model of focal cerebral ischemia .In the process of preparation , it is easy to be influenced by multiple factors;among them the successful operation plays a key role .This article summarized from several aspects , such as the anatomic locations of the major arteries in the rat ’ s neck , where to perform the incision , which side to perform the operation and where to insert the suture .

关 键 词：大鼠 线栓法 脑缺血模型 大脑中动脉闭塞 

分 类 号：Q95-336[生物学—动物学] R332[医药卫生—人体生理学]