运动时间诱导大鼠Resistin表达差异的研究  

Effects of different exercise duration on Resistin content in T2DM rats

作　　者：刘淑梅[1] 王耀光[2] 李梅月[1] 

机构地区：[1]山东科技大学体育学院,山东青岛266590 [2]辽宁师范大学体育学院,辽宁大连116029

出　　处：《山东体育科技》2014年第4期71-74,共4页Shandong Sports Science & Technology

摘　　要：以观察不同运动持续时间对大鼠Resistin蛋白表达的影响为主要研究目的,经2型糖尿病大鼠建模后,将62只正常及糖尿病大鼠分为6组:正常对照组,糖尿病对照组和糖尿病运动4组(20、40、60和80分钟组)。在运动组大鼠进行一次中等强度的跑台运动后,用SDS-聚丙烯酰胺凝胶电泳法检测大鼠蛋白的表达情况。与糖尿病对照组相比表明各运动组Resistin蛋白含量显著下降(P<0.01);与20分钟和40分钟组相比,60分钟组下降的幅度具有显著性差异(P<0.01和P<0.05)。由此得出结论:持续运动达60分钟的中等强度运动对Resistin蛋白表达的影响好于其他运动时间。To explore the effects of different duration of exercise on Resistin protein expression in rats with type 2 diabetes is the main objective for this paper. 62 SD normal and type 2 diabetes rats were divided into 6 groups：normal control group,diabetes mellitus group,20 min group,40 min group,60 min group and 80 min group. After one - bout exercise with moderate intensity for the exercise groups,the contents of Resistin protein were measured by SDS -PAGE. The contents of Resistin protein in exercise groups decreased（P ﹤ 0. 01）respectively compared with the diabetes mellitus group;The contents of Resistin protein in 60 min group decreased significantly compared with 20 min and 40 min group（P ﹤ 0. 01 and P ﹤ 0. 05）. A conclusion can be obtained that the effect of 60 min exercise duration on the expression of Resistin protein is better than that of any other exercise duration.

关 键 词：运动持续时间 2 型糖尿病大鼠 RESISTIN 

分 类 号：G804.7[文化科学—运动人体科学]