不同烃链长度咪唑类离子液体对日本三角涡虫的急性毒性  

Acute Toxicity of Imidazolium Ionic Liquids with Different Alkyl-chain Lengths to Planarian Dugesia japonica

作　　者：石长应[1] 王凡[1] 张合彩[1] 陈广文[1] 刘德增[1] 

机构地区：[1]河南师范大学生命科学学院,河南新乡453007

出　　处：《河南师范大学学报（自然科学版）》2014年第4期178-182,188,共6页Journal of Henan Normal University(Natural Science Edition)

基　　金：国家自然科学基金(31170357;30870368;30670247;30170119);教育部高等学校博士点基金(200804760003);河南省杰出青年基金(0312001100);河南省自然科学基金(122300410141);河南师范大学青年骨干教师基金(521)

摘　　要：采用SPSS软件概率单位法研究了4种不同烃链长度的咪唑类离子液体对日本三角涡虫的急性毒性.结果表明:[C4mim]Br,[C6mim]Br,[C8mim]Br和[C10mim]Br对日本三角涡虫72h、96h的半数致死浓度(LC50)分别为2 079.46和1 744.38mg·L-1,919.35和725.00mg·L-1,312.79和238.50mg·L-1以及32.57和23.25mg·L-1.由LC50值的大小可知,4种不同烃链长度的咪唑类离子液体的毒性[C10mim]Br>[C8mim]Br>[C6mim]Br>[C4mim]Br.由此可见,咪唑类离子液体对涡虫的急性毒性大小与其烷基侧链长度密切相关,碳链越长毒性越大.此外,根据急性毒性试验涡虫的中毒症状,也就离子液体对涡虫可能的靶器官问题进行了初步探讨.The acute toxicity to planarian Dugesia japonica of imidazolium ionic liquids with varying alkyl chain lengths was evaluated by probit method via SPSS13.0 for Windows. The results show that the LC50 （72 h） and LC50 （96 h） values of [C4mim]Br, [C6mim]Br, [C8mim]Br and [C10mim]Br to D. japonica are 2 079.46 and 1 744.38 mg·L-1, 919.35 and 725.00 mg·L^-1, 312.79 and 238.50 rag. L 1, 32.57 and 23.25 mg·L^-1 respectively. According to the LCs0 values, the toxicity Of [C10 mim]Br is the strongest and that of [C4 mim]Br is the weakest. This indicats the acute toxicity of different ILs to planarian is related to the length of its side chain, the longer the side chain, the stronger the toxicity. Furthermore, based on the symptoms of poisoning, the problem concerning the target of IL to planarian was also primary discussed.

关 键 词：离子液体 日本三角涡虫 急性毒性 半数致死浓度 

分 类 号：Q95[生物学—动物学]