临床路径对抑郁症患者医院感染的影响  

Effect of clinical pathway on nosocomial infections in patients with depression

作　　者：吴怀能[1] 严涓[1] 张丽英[1] 马黎君[1] 练亚芬[1] 

机构地区：[1]杭州市第七人民医院医务科,浙江杭州310013

出　　处：《中华医院感染学杂志》2014年第18期4540-4542,共3页Chinese Journal of Nosocomiology

基　　金：浙江省杭州市卫生科技基金资助项目(2011A045)

摘　　要：目的探讨临床路径治疗对抑郁症患者医院感染的影响,为临床控制抑郁症患者医院感染提供依据。方法将120例抑郁症患者随机均分为观察组和对照组,每组各60例,观察组应用临床路径进行治疗,对照组以常规模式进行治疗,对两组患者的感染率、感染知识掌握程度、治疗依从性等进行对比分析;采用SPSS13.0软件对数据进行统计分析,计数资料采用χ2检验,计量资料用t检验。结果 120例抑郁症患者中发生医院感染9例,感染率为7.5%,观察组发生医院感染3例次,例次感染率5.0%,对照组发生医院感染10例次,例次感染率16.7%,两组比较差异有统计学意义(P<0.05);感染部位以呼吸道感染为主,占53.85%,其次为泌尿道和胃肠道,分别占23.08%和15.38%;共分离出病原菌33株,前3位病原菌依次为肺炎克雷伯菌、大肠埃希菌、金黄色葡萄球菌,分别占51.52%、27.27%、18.18%;观察组在住院天数、出院时对感染知识掌握程度、出院时抑郁得分、出院时对治疗的依从性、联合用药等5个方面均明显好于对照组(P<0.05)。结论临床路径治疗可减少抑郁症患者的住院天数、规范治疗、合理用药、提高感染知识知晓率及治疗依从性等,从而降低抑郁症患者的医院感染率。OBJECTIVE To explore the effect of clinical pathway on nosocomial infections in the patients with de-pression so as to provide guidance for clinical control of nosocomial infections in the depression patients . METHODS A total of 120 depression patients were randomly divided into the observation group and the control group ,with 60 cases in each ;the observation group was treated with clinical pathway ,while the control group was treated with conventional mode ;the incidence of infections ,awareness of knowledge of infections ,and com-pliance to treatment were observed and compared between the two groups of patients ,the data were statistically analyzed by using SPSS13 .0 software ,the count data were analyzed with the use of Chi-square test ,and the meas-urement data were analyzed by means of t-test .RESULTS The nosocomial infections occurred in 9 of 120 depression patients ,with the infection rate of 7 .5% ;the nosocomial infections occurred in 3 （5 .0% ） case-times in the obser-vation group ,10 （16 .7% ） case-times in the control group ,and there was significant difference between the two groups （P〈0 .05） .Among the patients with nosocomial infections ,the patients with respiratory tract infections accounted for 53 .85% ,the patients with urinary tract infections 23 .08% ,the patients with gastrointestinal tract infections 15 .38% .Totally 33 strains of pathogens have been isolated ,among which the K lebsiella pneumoniae , Escherichia coli ,and Staphylococcus aureus ranked the top three species of pathogens ,accounting for 51 .52% , 27 .27% ,and 18 .18% ,respectively .The hospitalization duration ,awareness of knowledge of infections at the dis-charge ,depression score at the discharge ,compliance to treatment at the discharge ,and combination medication of the observation group were significantly better than those of the control group （P〈 0 .05） .CONCLUSION The clinical pathway can contribute to the reduction of hospitalization duration ,standardized treatment ,reasonable medication ,and i

关 键 词：临床路径 抑郁症 医院感染 

分 类 号：R181.32[医药卫生—流行病学]