宫颈癌患者术后医院感染相关危险因素分析  

Analysis of the associated risk factors for postoperative infections in patients with cervical cancer

作　　者：刘瑶[1] 赵光宗[1] 车力凡[1] 张华朋[1] 

机构地区：[1]潍坊市益都中心医院妇产科,山东潍坊262500

出　　处：《中华医院感染学杂志》2014年第18期4612-4613,4616,共3页Chinese Journal of Nosocomiology

基　　金：国家自然科学基金资助项目(30974132)

摘　　要：目的探讨宫颈癌患者术后发生感染的相关危险因素,为减少患者术后感染提供理论依据。方法回顾性分析2010年12月-2012年12月150例宫颈癌患者的临床资料,对发生感染的患者的临床资料进行单因素分析和多因素logistic回归分析,观察发生感染的相关危险因素,采用SPSS17.0软件进行统计分析。结果 150例患者术后发生感染46例,感染率为30.67%,以泌尿系统、阴道残端和盆腔感染为主;单因素分析发现,患者的年龄、病理类型、宫颈癌分期、基础疾病≥3种、化疗药物、术后导尿次数、导尿管留置时间、手术时间以及术后抗菌药物使用等有显著相关性(P<0.05);多因素logistic回归分析显示,患者的年龄、宫颈癌分期、进行化疗治疗、术后导尿次数以及导尿管留置时间等是宫颈癌患者术后发生感染的独立危险因素。结论宫颈癌患者术后发生感染的危险因素较多,应引起高度重视并进行针对性干预处理。OBJECTIVE To study the associated risk factors for postoperative infections in patients with cervical cancer so as to provide theoretical basis for reducing infection after cervical cancer surgery .METHODS Clinical data of 150 patients with cervical cancer from Dec .2010 to Dec .2012 in our hospital were retrospectively analyzed .The univariate analysis and the multivariate logistic regression analysis were conducted on the clinical data of infected patients ,infection-related risk factors were observed ,and SPSS 17 .0 software was used for statistical analysis .RESULTS Totally 46 in 150 patients had postoperative infection ,the rate was 30 .67% ,mainly with infections in urinary tract and vaginal stump and pelvic cavity . The univariate analysis showed that the patient′s age ,histological types ,cancer stages ,more than 3 underlying diseases ,chemotherapy drugs ,the num-ber of postoperative catheterization ,catheter indwelling time ,operative time and postoperative antibiotic use had significant association （P＆lt;0 .05） .The multivariate logistic regression analysis revealed that the patient′s age , cancer stages ,chemotherapy treatment ,the number of postoperative catheterization ,catheter indwelling time were independent risk factors for postoperative infection in cervical cancer patients .CONCLUSIONS There are many risk factors for postoperative infection in patients with cervical cancer .The doctors should pay close attention and perform targeted interventions .

关 键 词：宫颈癌 医院感染 危险因素 

分 类 号：R619.3[医药卫生—外科学]