草酸钙肾结石成因的研究现状  

Research Causes of Calcium Oxalate Kidney Stones Causes

作　　者：田爱民[1] 安瑞华[1] 杨磊[1] 林洋[1] 余彪[1] 

机构地区：[1]哈尔滨医科大学第一临床医学院泌尿外科,黑龙江哈尔滨150001

出　　处：《现代生物医学进展》2014年第27期5394-5396,共3页Progress in Modern Biomedicine

摘　　要：肾结石是一种全球性疾病,同时也是泌尿外科最常见的疾病之一。近年来,肾结石在我国的发病率有逐渐上升趋势,大约5%-15%的人群一生中会罹患肾结石,其中约80%为草酸钙肾结石。多数草酸钙肾结石患者没有发现伴有其他系统疾病的存在,称为特发性草酸钙肾结石;一些患者存在原发性甲状旁腺功能亢进或其他钙代谢异常性疾病;一些患者主要表现为高草酸尿症等。虽然近年来体外冲击波碎石和内腔镜技术的发展使本病的治疗取得了很大的进展,然而,肾结石的复发率仍居高不下,10年复发率可达50%,20年的复发率可达75%。因此,如何有效地预防结石发生和降低复发率,成为当前研究的重点内容。这对于制定恰当的、个性化的预防方案有重要价值。Kidney stones are a global disease,but also one of the most common diseases of Urology. Recently, there is a gradual upward trend in the incidence of kidney stones in China ＇s. About 5 % -15 % of the population will suffer from kidney stones, which approximately 80% of calcium oxalate stones. Most CaOx kidney stone patients is not associated with the presence of other systemic diseases, called idiopathic calcium oxalate stones; Some patients with primary hyperparathyroidism or other calcium metabolic, some with hyperoxaluria, etc. Extracorporeal Shock Wave Lithotripsy and Endoscopic technology development made great progress in the treatment of this disease in recent years, however, the recurrence rate of kidney stones is high and new patients each year continues to increase, 10-year recurrence rate is up to 50%, and 20-year recurrence rate is up to 75%. Therefore, how to effectively prevent stone formation and reduce the relapse rate, become the focus of the current study, which has important value for appropriate and personalized prevention programs is important value.

关 键 词：草酸钙结石 病因 危险因素 

分 类 号：R692.4[医药卫生—泌尿科学]