以中枢神经系统受累为首发表现的干燥综合征1例并文献复习  

Primary Sjgren Syndrome with Central Nervous System Disorder:a Case Report and Review of Literature

作　　者：李婉[1] 高婷婷[1] 张鲁宁[1] 吴艺虹[1] 郑志超[2] 赵岩[2] 

机构地区：[1]沈阳医学院奉天医院风湿免疫科,辽宁沈阳110024 [2]辽宁省肿瘤医院大连医科大学附属临床肿瘤学院胃外科,辽宁沈阳110042

出　　处：《现代生物医学进展》2014年第28期5562-5564,共3页Progress in Modern Biomedicine

基　　金：2011年度国家人力资源社会保障部留学人员科技活动项目择优资助(2011LX005);2011辽宁省自然科学基金(201102110)

摘　　要：目的:提高对干燥综合征中枢神经系统损害的认识,了解其特点及治疗。方法:报告1例以中枢神经系统受累为首发表现的干燥综合征病例,并对相关文献进行复习。结果:此例患者以脊髓病变为首发症状,长期口干、眼干,查体及实验室等相关检查诊断干燥综合征明确。结论:干燥综合征可存在中枢神经系统损害,其中脊髓病变较常见,应注意完善影像学及脑脊液检查,并与系统性红斑狼疮等结缔组织病相鉴别。Objective： To better understand the clinical features and treatment of primary Sjogren Syndrome with central nervous system disorder. Methods： Report a case of central nervous system involvement as the first manifestation of primary Sjogren Syndrome and reviewed the related literature. Results： This patient with spinal cord lesions as the first symptoms, with long-term dry mouth, dry eyes and the examination and laboratory diagnosis of primary Sjogren Syndrome clear. Conclusion： The primary Sjogren Syndrome can exist in damage to the central nervous system, especially the spinal cord lesions. We should pay attention to the imaging and cerebrospinal fluid examination and identify with the connective tissue disease such as systemic lupus eythematosus.

关 键 词：干燥综合征 中枢神经系统 

分 类 号：R725.2[医药卫生—儿科]