中西医结合治疗冠心病合并焦虑症临床疗效及不良反应观察  

Integrative Medicine Clinical Efficacy of Coronary Heart Disease and Anxiety Disorders and Adverse Reactions

作　　者：方晓江[1] 钱宝庆[1] 赵芊[1] 魏丽萍[1] 陈启兰[1] 

机构地区：[1]杭州市中医院心内科,浙江杭州310007

出　　处：《中华中医药学刊》2014年第9期2299-2301,共3页Chinese Archives of Traditional Chinese Medicine

摘　　要：目的:探讨中西医结合治疗冠心病合并焦虑症临床疗效及不良反应观察,为临床诊断治疗提供依据。方法:将本组95例冠心病合并焦虑症患者根据随机数字表法随机分为对照组(n=45)和治疗组(n=50)。对照组在常规治疗基础上口服黛力新;治疗组在对照组治疗基础上服用自拟中药汤剂进行治疗。结果:治疗组治疗后临床症状总有效率(92.00%)显著高于对照组(75.56%),且有显著性差异(P<0.05);治疗组治疗后心电图总有效率(74.00%)显著高于对照组(53.33%),且有显著性差异(P<0.05);两组治疗前平均心率与HAMA评分比较均无显著性差异(P>0.05);治疗后治疗组平均心率与对照组比较,无显著性差异(P>0.05);治疗后治疗组HAMA评分显著低于对照组,且有显著性差异(P<0.05);两者患者治疗后均未发生明显不良反应。结论:中西医结合治疗冠心病合并焦虑症取得了明显的临床效果,很好的改善了患者焦虑情绪,且无明显不良发应发生,具有重要的临床研究价值。Objective ： To investigate the integrative treatment of coronary artery disease： and anxiety and adverse reactions and to provide the basis for clinical diagnosis and treatment. Methods ： 95 cases of coronary heart disease and anxiety disorders were randomly divided into control group （ n = 45 ） and treatment group （ n = 50） according to the random number table. Deanxit was used in control group and treatment group took the self - made decoction for treatment on the control group basis. Results： After treatment, the treatment group＇s total efficiency （92.00%） was significantly higher than that of control group （75.56%）and there was a significant difference（P 〈 0.05 ）. After treatment, electrocardiogram overall response rate （74.00%） was significantly higher than that in the control group （53.33%） and there was a significant difference （P 〈0.05）. Before treatment, the average heart rate and HAMA score showed no significant difference between two groups （P 〉0.05 ）. The treatment group and the control group＇s average heart rates after treatment had no significant difference （P 〉 0.05 ）. HAMA score after the treatment in the treatment group was significantly lower than that of the control group and there was significant difference （ P 〈 0.05 ）. There was no significant adverse reaction. Conclusion： The combination therapy of anxiety disorders in coronary artery disease achieved significant clinical effects, relieved patients＇ anxiety mood and had no significant adverse reaction with important clinical research value.

关 键 词：冠心病 焦虑症 中西医 疗效 不良反应 

分 类 号：R541.4[医药卫生—心血管疾病]