上海市长宁区男男性行为人群梅毒感染情况及其危险因素分析  

Analysis on the syphilis infections and risk factors among men who have sex with men in Changning District of Shanghai

作　　者：朱晓华[1,2] 沈利[1,2] 尹宁[2] 倪莹青[2] 郑敏[2] 王震宇[2] 

机构地区：[1]同济大学医学院病原生物学教研室,上海200092 [2]上海市长宁区疾病预防控制中心性艾结防科

出　　处：《中华实验和临床感染病杂志（电子版）》2014年第4期40-43,共4页Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)

摘　　要：目的通过对上海市长宁区男男性行为（MSM）人群梅毒感染情况及其危险因素分析，为有效遏制梅毒等经性传播疾病疫情提供有针对性的干预措施。方法对经上海市长宁区疾病预防控制中心自愿咨询检测（VCT）门诊检测咨询的MSM进行面对面问卷调查，并分析其梅毒感染情况及危险因素。结果自2011年11月至2013年3月共调查符合要求的对象231例。经检测，231例调查对象中梅毒感染者56例，占24．24％，其中现症梅毒感染18例，占7。79％。经问卷调查分析得出尖锐湿疣感染者占7．36％（17／231）；18例现症梅毒感染者中，15例（83．33％）合并感染HIV，2例（11．11％）合并感染尖锐湿疣。经单因素分析发现，不同年龄、婚姻状态、文化程度和性伴情况，其梅毒感染情况不刚，芹异具有统计学意义（P均〈0．05）；经多因素非条件Logistic回归分析结果显示，性伴情况对梅毒感染有显著影响（OR=0．088，95％CI：0．029～0．272），有偶遇同性性伴的MSM梅毒感染率更高。结论到本区检测咨询的MSM梅毒感染率高，还存在一定比例的性病混合感染，有偶遇同性性伴的MSM梅毒感染率更高。应加大对有偶遇同性性伴的MSM人群的宣传力度，强调坚持每次使用安全套的重要性，树立高度的风险意识，让其克服侥幸心理，从而降低梅毒等经性传播疾病感染率。Objective To analyze syphilis infections and risk factors among men who have sex with men （MSM） in Changning District of Shanghai and afford efficient intervening measure of containing epidemic situation. Methods MSM to test and counsel from voluntary counseling and testing （VCT） in Changning CDC of Shanghai were interviewd with face to face questionnaires. The syphilis infections and risk factors were analyzed, restrospectively. Results A total of 231 MSM participated in the survey conducted from November 2011 to March 2013. Among the 231 participants, 24.24% （56/231） were seropositive for syphilis infection with TP-ELISA test and 7.79% （18/231） for active syphilis. An overall prevalence of 7.36% （17/231） for condyloma acuminata （CA） was found with questionnaire survey. There were 15 （83.33%） cases for HIV-positive and 2 （11.11%） cases for CA-positive among 18 participatients with active syphilis. There were significant differences between age, marriage, degree of education, sex partner and syphilis infection with single factor analysis （P all 〈 0.05）. Multivariate analysis revealed that syphilis infection was associated with different sex partner conditions. The rate of syphilis infection was higher among MSM who have occational homosexual partners （OR - 0.088, 95%CI： 0.029-0.272）. Conclusions The rate of syphilis infection was high among MSM （particularly among MSM who have occational homosexual partner） to test and counsel from VCT in Shanghai Changning CDC. In future, we should manage to emphasis the importance of insisting on using condom every time, and let MSM establish consciousness of risk highly and overcome invulnerability.

关 键 词：男男性行为人群 梅毒 危险因素 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]