两种大孔吸附树脂对麻黄碱和伪麻黄碱的吸附动力学和热力学研究  

ADSORPTION KINETICS OF EPHEDRINE AND PSEUDO EPHEDRINE ON TWO TYPES OF MACROPOROUS RESINS

作　　者：索绪斌[1] 王文青[2] 徐兴[1] 张涵 

机构地区：[1]广东药学院中药学院,广州510006 [2]湖北省荆州市中心医院药剂科,荆州4340203 [3]黑龙江省中医药科学院,哈尔滨150036

出　　处：《离子交换与吸附》2014年第4期350-358,共9页Ion Exchange and Adsorption

基　　金：国家自然科学基金(30973954);国家科技创新基金(国科发计[2013]583号)

摘　　要：通过等温静态吸附实验研究大孔树脂AB-8和D101对麻黄碱及伪麻黄碱的等温吸附过程,根据Langmuir平衡吸附速率方程考察两种树脂对两种成分吸附的平衡速率常数,用Van’t Hoff公式计算各热力学参数(ΔHm,ΔGm及ΔSm)。结果表明麻黄碱、伪麻黄碱的吸附平衡数据符合Freundlich吸附等温方程和Langmuir平衡吸附速率方程,相关性良好。吸附的焓变(ΔHm)和熵变(ΔSm)均大于零,吉布斯自由能变(ΔGm)均小于零,表明麻黄碱及伪麻黄碱在树脂上的吸附属于自发的物理吸附过程。Isothermic adsorptions of ephedrine and pseudo ephedrine on two types ofmacroporous resins, AB-8 and D101, were preliminarily examined, and the experimental datawere fitted by Langmuir model. Thermodynamic parameters （AHm, AGm and ASm） werecalculated according to Van＇t Hoff equation. The adsorptions of ephedrine and Pseudo ephedrineon macroporous resins of AB-8 and D101 were also studied. The experimental results ofadsorption kinetics showed that the data complied with the Freundlich adsorption isothermequation and Langrnuir equilibrium adsorption rate equation. Adsorption enthalpy change （AHm）and entropy change （ASm） were greater than zero, while Gibbs energy change （AGm） was lessthan zero, which indicated that ephedrine and Pseudo ephedrine adsorbed on the resins werespontaneously physical adsorption process.

关 键 词：麻黄碱 伪麻黄碱 大孔吸附树脂 吸附动力学 

分 类 号：O643.7[理学—物理化学]