某院清洁手术围手术期预防性应用抗菌药物干预前后对比分析  

Comparative study of the application of prophylactic antibacterial agents on clean surgery between before and after the antibacterial intervention

作　　者：刘敏[1] 徐小芳[1] 朱春黎[1] 康圆超 安志红[2] 

机构地区：[1]上海市第二人民医院药剂科,上海200011 [2]上海市第二人民医院ICU,上海200011

出　　处：《安徽医药》2014年第11期2195-2198,共4页Anhui Medical and Pharmaceutical Journal

摘　　要：目的调查干预前后该院清洁手术围手术期预防性应用抗菌药物的情况,为临床合理用药提供参考。方法随机抽取该院2011年1—6月Ⅰ类切口手术出院病历36份(干预前组),2012年1—6月Ⅰ类切口手术出院病历46份(第一阶段干预后组),2013年1—6月Ⅰ类切口手术出院病历33份(第二阶段干预后组),对比分析持续干预前后抗菌药物预防应用情况。结果经积极持续干预,与2011年相比,该院清洁手术围手术期抗菌药物使用率由97.2%下降到18.2%、术后24 h内抗菌药物使用率由40.0%上升到83.3%,人均抗菌药物总费用占药品总费用的比也由13.66%降为2.66%。结论经过2个阶段的积极干预措施是可行的、有效的,该院清洁手术围手术期抗菌药物使用情况得到明显改善。Objective To analyze the clinical effect of the two-stage intervention approach of prophylactic antibacterial drugs using during perioperative period of the clean surgery,and to provide references for proper use of antibacterial drugs in clinic. Methods Da-ta of the antibacterial drugs usage were collected from the individual three different groups： one group of pre-intervention data was gained from 36 cases of type I incision operations conducted between January and June,2011. The other two groups of post-intervention data were gained from the 46 cases of type I incision operations （ first phase） from January to June,2012 and from the 33 cases of type I incision operations （second phase） between January and June,2013. Results Compared with pre-intervention in 2011,the percent-age of prophylactic use of antibiotics decreased from 97. 2% to 18. 2% after intervention. The usage rate of antibiotics in the 24 hour post-operation rose from 40. 0% to 83. 3%. The ratio of the per capita total cost of antibacterials to the total cost of hospital drugs de-creased from 13. 66% to 2. 66%. Conclusions The two-stage active intervention was proved to be practicable and effective in impro-ving the efficacy of prophylactic administration of antibacterial drugs for clean surgery.

关 键 词：清洁手术 抗菌药物 干预 

分 类 号：R95[医药卫生—药学]