缩宫素和米索前列醇联合防治产后出血的疗效观察  

Curative Effect of Oxytocin Combined with Misoprostol in Treatment of Postpartum Hemorrhage

作　　者：汪昌平[1] 

机构地区：[1]霍山县医院,安徽霍山237200

出　　处：《中外医学研究》2014年第26期25-26,共2页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探究缩宫素和米索前列醇联合治疗产后出血的临床效果。方法:2010年1月-2013年12月在笔者所在医院收治的产后出血患者共60例,按照随机数字表法分成对照组和观察组,每组30例。对照组给予缩宫素治疗,观察组给予缩宫素和米索前列醇的联合治疗,观察两组患者产后2 h、24 h的出血量并观察两组患者有无不良反应的发生率来评定治疗效果。结果:治疗后观察组患者产后2 h、24 h的出血量均明显少于对照组,比较差异有统计学意义(P<0.05);治疗后观察组不良反应的发生率为13.33%,对照组为10.00%,两组比较差异无统计学意义(P>0.05)。结论:缩宫素和米索前列醇联合应用,能有效控制产后2 h、24 h的出血量,不良反应的发生率较低,安全系数高。Objective：To investigate the curative effect of Oxytocin combined with Misoprostol in treatment of postpartum hemorrhage.Method：Sixty cases of postpartum hemorrhage patients were treated in our hospital from January 2010 to January 2014,and were randomly divided into the control group and observation group,each group of 30 cases.Patients in the control group received Oxytocin treatment,while patients in the observation group received the combination therapy of Oxytocin and Misoprostol.2 h,24 h bleeding and adverse reaction rates of two groups’patients were observed to evaluate the therapeutic effect.Result：After treatment,postpartum 2 h,24 h bleeding of observation group patients were significantly less than that in the control group,and the difference were statistically significant （P〈0.05）.After treatment,the adverse reaction rate in observation group was 13.33%,while the adverse reaction rate in control group was 10.00%, and the difference was not statistically significant （P〉0.05）.Conclusion：Combination therapy of Oxytocin and Misoprostol can effectively control the postpartum hemorrhage volume of 2 h,24 h,has a low incidence rate of adverse reaction,and has a high safety coefficient.

关 键 词：缩宫素 米索前列醇 产后出血 

分 类 号：R714.461[医药卫生—妇产科学]