补阳还五汤结合西药治疗脑血栓  

Observation on Clinical Efficacy of Buyang Huanwu Decoction in Treating Cerebral Thrombosis

作　　者：陶恩学[1] 高汉义[2] 

机构地区：[1]潍坊医学院校医院,山东潍坊261053 [2]潍坊医学院附属医院中医科,山东潍坊261053

出　　处：《中国实验方剂学杂志》2014年第18期181-183,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：山东省中医药扶持项目([2009]415号)

摘　　要：目的:研究补阳还五汤治疗脑血栓的临床效果,为今后的临床工作提供参考依据。方法:选取100例脑血栓患者,按照治疗方法的不同分为对照组与观察组,对照组给予西医常规治疗,观察组在对照组治疗的基础上给予补阳还五汤治疗,组方:黄芪60 g,桃仁10 g,川芎10 g,当归尾10 g,红花9 g,赤芍9 g,地龙9 g;患者若伴有神志不清则加石菖蒲10 g;患者若伴有头晕烦躁加白芍10 g,生牡蛎、生龙骨各30 g;患者若伴有大便不通加大黄10 g,若患者伴有痰浊加胆南星与法半夏各10 g。观察两组患者治疗后的临床疗效及生活质量的改善情况。结果:两组患者疗效总有效率的比较P<0.05;经治疗后生活基本自理的比较P<0.01;生活严重不能自理的比较P<0.05;两组患者经治疗后红细胞压积比较P<0.01;全血黏度比较P<0.01;纤维蛋白原比较P<0.01,差异具有统计学意义;生活需要帮助的比较无显著差异。结论:补阳还五汤治疗脑血栓效果显著,安全性高,且无不良严重反应发生,值得临床推广使用。Objective：The purpose of this research was to study clinical efficacy of Buyang Huanwu decoction in treating cerebral thrombosis,and to provide a reference basis for clinical work in the future.Method：One hundred patients with cerebral thrombosis admitted were divided into the control group and the observation group according to different treatment methods.The patients in the control group were subject to conventional western medicine treatment,and the patients in the observation group were subject to the western medicine treatment combined with Chinese medicine treatment （Buyang Huanwu decoction treatment on the basis of the treatment applied on patients in the control group）,then clinical efficacy and improvements of life quality of patients in two groups were observed.Result：As for the total effective rate of patients in two groups （P ＜ 0.05）,the basic self-care of life after treatment （P ＜ 0.01）,the seriously unable self-care of the life （P ＜ 0.01）,the hematokrit of patients in two groups after treatment （P ＜ 0.01）,the whole blood viscosity （P ＜ 0.01）,and the fibrinogen （P ＜0.01）,all the differences were statistically significant; and for the assistance of life needed,there was no significant difference.Conclusion：The Buyang Huanwu decoction delivers significant effect and high safety on treating cerebral thrombosis,and no serious adverse reaction was detected,which is worthy of clinical promotion.

关 键 词：补阳还五汤 西医 常规治疗 脑血栓 

分 类 号：R287.6[医药卫生—中药学]