月经病实寒证患者卵巢子宫血流动力学变化及对生殖激素的影响  

Hemodynamic changes of ovary and uterus and their influences on reproductive hormones in patients with emmeniopathy(excess cold syndrome)

作　　者：刘小花[1] 杜惠兰[1] 成秀梅[1] 路帅[2] 苏健[2] 楚健子[3] 孙梅 王蓓[1] 

机构地区：[1]河北中医学院,河北050091 [2]石家庄市中医院 [3]河北省中医院 [4]石家庄妇产医院

出　　处：《北京中医药大学学报》2014年第8期568-571,共4页Journal of Beijing University of Traditional Chinese Medicine

基　　金：国家自然科学基金资助项目(No.30973766;81373514);河北省科技资助项目(No.132777128D)

摘　　要：目的观察月经病实寒证患者卵巢子宫血流动力学变化,探讨月经病实寒证发生的病理机制。方法设正常对照组和患者组各30例,应用彩色多普勒超声测定卵巢及子宫动脉血流参数:收缩期峰值流速(PSV)、阻力指数(RI)、搏动指数(PI);采用放射免疫分析方法测定血清孕酮(P)、雌二醇(E_2)、卵泡刺激素(FSH)、黄体生成素(LH)含量,进行对比分析。结果患者组卵巢及子宫动脉血流信号相对稀疏,流速过低,PSV显著降低(P<0.01),RI、PI升高(P<0.01或P<0.05);血清FSH、LH、E_2水平显著降低(P<0.01)。结论卵巢子宫的血流动力学异常,血液灌注不足,是月经病实寒证发生的病理基础之一。Objective To observe the hemodynamic changes of ovary and uterus in the patients with emmeniopathy （excess cold syndrome）,and discuss the pathogenesis of emmeniopathy （excess cold syndrome）.Methods The patients were divided into control group and patient group （each n =30）.The hemodynamic parameters of ovary and uterus were detected by using color Doppler ultrasound including peak systolic velocity （PSV）,resistance index （RI） and pulsatility index （PI）.The content of serum progesterone （P）,estradiol （E2）,follicle stimulating hormone （FSH） and luteinizing hormone （LH） were detected by using radioimmunoassay （RIA）.All data was compared and analyzed.Results In patient group,the hemodynamic signals of ovary and uterus were relative sparse,flow rate was lower,and PSV decreased significantly （P 〈 0.01）,RI and PI increased （P 〈 0.01 or P 〈 0.05）,and levels of serum FSH,LH and E2 decreased significantly （P 〈 0.01）.Conclusion The abnormal hemodynamics of ovary and uterus and blood hypoperfusion are one of pathological bases of emmeniopathy （excess cold syndrome）.

关 键 词：月经病实寒证 卵巢动脉血流动力学 子宫动脉血流动力学 生殖激素 

分 类 号：R271.1[医药卫生—中医妇科学]