Elevated Resting Heart Rate is Associated with Dyslipidemia in Middle-aged and Elderly Chinese  

作　　者：SUN Ji Chao HUANG Xiao Lin DENG Xin Ru LV Xiao Fei LU Jie Li CHEN Yu Hong BI Yu Fang WANG Wei Qing XU Min NING Guang 

机构地区：[1]Key Laboratory for Endocrine and Metabolic Diseases, Ministry of Health, Ruijin Hospital, Shanghai Jiaotong University School of Medicine,E-Institute of Shanghai Universities [2]Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases,Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine [3]Laboratory of Endocrine and Metabolic Diseases, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, and Shanghai Jiaotong University School of Medicine

出　　处：《Biomedical and Environmental Sciences》2014年第8期601-605,共5页生物医学与环境科学（英文版）

基　　金：supported by grants from the Key Laboratory for Endocrine and Metabolic Diseases of Ministry of Health(1994DP131044);National Nature Science Foundation of China(81170739,81170719,81270877,81222008);Shanghai New Excellent Youth Program(XYQ2011009);the Shanghai Health Bureau Grant(2011293)

摘　　要：Objective To study the relationship between resting heart rate and blood lipid level. Methods A total of 9 415 subjects aged≥40 years were included in the present study. Their resting heart rate was monitored and their serum levels of triglyceride （TG）, total cholesterol （TC）, low density lipoprotein cholesterol （LDL-C） and high density lipoprotein cholesterol （HDL-C） were measured to define dyslipidemia according to the 2007 Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults. Results The subjects were divided into group A with their resting heart rate〈70 beats/min, group B with their resting heart rate=70-79 beats/min, group C with their resting heart rate=80-89 beats/min, and group D with their resting heart rate≥90 beats/min. High TG, TC, and LDL-C were presented across the resting heart rate （Ptrend〈0.01）. Multiple logistic regression analysis revealed that the risk of high TG and TC was higher in subjects with their resting heart rate≥90 beats/min than in those with their resting heart rate〈70 beats/min （OR=1.42;95%CI：1.16-1.74 and OR=1.33;95%CI：1.09-1.64, respectively）. Conclusion Elevated resting heart rate is associated with high TG and TC in middle-aged and elderly Chinese subjects.Objective To study the relationship between resting heart rate and blood lipid level. Methods A total of 9 415 subjects aged≥40 years were included in the present study. Their resting heart rate was monitored and their serum levels of triglyceride （TG）, total cholesterol （TC）, low density lipoprotein cholesterol （LDL-C） and high density lipoprotein cholesterol （HDL-C） were measured to define dyslipidemia according to the 2007 Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults. Results The subjects were divided into group A with their resting heart rate〈70 beats/min, group B with their resting heart rate=70-79 beats/min, group C with their resting heart rate=80-89 beats/min, and group D with their resting heart rate≥90 beats/min. High TG, TC, and LDL-C were presented across the resting heart rate （Ptrend〈0.01）. Multiple logistic regression analysis revealed that the risk of high TG and TC was higher in subjects with their resting heart rate≥90 beats/min than in those with their resting heart rate〈70 beats/min （OR=1.42;95%CI：1.16-1.74 and OR=1.33;95%CI：1.09-1.64, respectively）. Conclusion Elevated resting heart rate is associated with high TG and TC in middle-aged and elderly Chinese subjects.

关 键 词：DYSLIPIDEMIA Heart rate Triglyceride  Chotesterol 

分 类 号：R589.2[医药卫生—内分泌]