冬病夏治穴位贴敷治疗对慢性支气管炎患者血清炎症介质水平的影响  

The effects of acupoint sticking therapy in summer for winter disease on inflammation mediator in patients with chronic bronchitis

作　　者：丁元廷[1,2] 王玉文[1,2] 

机构地区：[1]贵州省中医医院 [2]贵阳中医学院第一附属医院检验科,贵州贵阳550001

出　　处：《国际检验医学杂志》2014年第17期2289-2290,共2页International Journal of Laboratory Medicine

基　　金：贵州省科学技术联合资金资助项目(黔科合中药字[2012]LKZ7040号);贵阳市社会发展与民生科技计划基金资助项目(筑科合同[2012103]45号)

摘　　要：目的通过检测慢性支气管炎患者冬病夏治穴位贴敷治疗前、后血清中白细胞介素-2(IL-2)、白细胞介素-4(IL-4)、白细胞介素-8(IL-8)、肿瘤坏死因子-α(TNF-α)等水平,探讨冬病夏治穴位贴敷疗法对人体血清IL-2、IL-4、IL-8、TNF-α水平的影响。方法将确诊为慢性支气管炎非急性期且未进行其他相关治疗的患者30例随机、平均分为穴位贴敷治疗组(治疗组)和对照组。治疗组给予"三伏贴"穴位贴敷疗法,对照组给予"安慰贴"穴位贴敷疗法;对比2组治疗前及治疗后的血清IL-2、IL-4、IL-8、TNF-α水平。结果在治疗组中,患者治疗后血清IL-2水平显著高于治疗前(P<0.05),IL-8、TNF-α水平显著低于治疗前(P<0.05);在治疗后,治疗组血清IL-2、IL-4水平显著高于对照组(P<0.05),IL-8、TNF-α显著低于对照组(P<0.05)。结论冬病夏治穴位贴敷治疗能有效提高慢支炎患者血清IL-2水平,降低IL-8、TNF-α水平,从而提高自身免疫调节能力,降低炎症发生程度。Objective By measuring the concentrations of serum IL-2,IL-4,IL-8 and TNF-αin chronic bronchitis patients before and after the acupoint sticking therapy which was also called winter disease treated in summer to investigate the effect of therapy on serum concentrations of IL-2,IL-4,IL-8 and TNF-α.Methods 30 cases of patients diagnosed with chronic bronchitis in paracmasia and did not recieve other related treatment were randomly divided into acupoint application therapy group （treatment group）and the control group.The treatment group was given＂three Fu＂acupoint sticking therapy,the control group was given the＂comfort＂acupoint sticking therapy.Serum IL-2,IL-4,IL-8 and TNF-αconcentrations were compared between the 2 groups before and after treatment.Results In the treatment group,the serum IL-2 concentration of patients after treatment was significantly higher than that before treatment（P 〈0.05）,IL-8 and TNF-αconcentrations were significantly lower than those before therapy（P 〈0.05）.Af-ter treatment,serum IL-2,IL-4 levels were significantly higher than those in the control group（P 〈0.05 ）while IL-8 and TNF-αwere significantly lower than those of the control group（P 〈0.05 ）.Conclusion Acupoint sticking therapy in summer for winter diseases effectively increase the concentration of serum IL-2 in patients with chronic bronchitis,reduced IL-8,TNF-α concentra-tions,and enhance their own immunity ability,reduce the degree of inflammation.

关 键 词：慢性支气管炎 冬病夏治 穴位贴敷疗法 炎症介质 

分 类 号：R245.9[医药卫生—针灸推拿学]