蛔虫重度流行区人群化疗策略的研究  

Research on chemotherapy strategy for population in heavy epidemic areas with ascaris iumbricoides

作　　者：谢峰 陈红根 曾小军 林丹丹 姜唯声 Jong-Yil Chai 

机构地区：[1]江西省寄生虫病防治研究所,南昌330046 [2]Seoul National University

出　　处：《江西医药》2014年第8期673-674,共2页Jiangxi Medical Journal

基　　金：韩国国际协力团资助(2001年)

摘　　要：目的评价不同化疗措施控制蛔虫的效果。方法在4个控制村用阿苯哒唑分别进行1年1次全民化疗、2年1次全民化疗、1年1次选择性化疗和1年2次选择性化疗措施后,连续4年观察其对控制居民蛔虫的效果,并和对照村进行比较。结果 2001年5个试点村蛔虫平均阳性率为44.37%(4850/10931),采取每1次/年全民化疗人群蛔虫感染率下降最大,由2001年的45.2%下降到2004年的6.3%,降幅为86.1%。结论 1次/年全民化疗策略对于控制蛔虫感染的效果佳。Objective To evaluate the effect of different chemotherapy strategies for Ascaris lumbricoides. Methods Four chemotherapy strategies with Albendazole,which were mass chemotherapy once a year,mass chemotherapy once in two years,se-lective chemotherapy once a year and selective chemotherapy twice a year,were carried out in four control villages,respectively. The effects of strategies on infection control of Ascaris lumbricoides were observed continuously for 4 years ,and compared with the dada of a control village. Results The average positive rate of Ascaris lumbricoides was 44.37%（4850/10931） in 5 pilot villages in 2001. The infection rate of Ascaris lumbricoides was decreased maximally,from 45.2%in 2001 to 6.3%in 2005 with the reduction of 86.1% in villages where the strategy of mass chemotherapy once a year was implemented. Conclusion The strategy of mass chemotherapy once a year has the best effect on infection control of Ascaris lumbricoides.

关 键 词：蛔虫 重度流行区 化疗 策略 

分 类 号：R532.11[医药卫生—内科学]