白癜风患者治疗前后血清中IL-10水平的变化  

Serum IL-10 levels in patients with vitiligo before and after treatment in Ningxia

作　　者：张莉[1] 陈阳[1] 汪京峡[2] 夏莉[2] 高琼[2] 

机构地区：[1]宁夏医科大学,宁夏银川750004 [2]宁夏医科大学总医院皮肤科,宁夏银川750004

出　　处：《宁夏医学杂志》2014年第9期817-819,共3页Ningxia Medical Journal

基　　金：宁夏自然科学基金资助项目(NZ13151)

摘　　要：目的探讨白癜风患者治疗前后血清中白介素10(IL-10)含量的变化及临床意义。方法采用ELISA法检测白癜风患者治疗前后血清中IL-10的含量。结果白癜风患者治疗前血清中IL-10的含量低于对照组,差异有统计学意义(t=7.80,P<0.05);治疗后IL-10含量明显高于治疗前,差异有统计学意义(t=-10.76,P<0.05)。结论白癜风患者治疗前后血清中IL-10的含量差异有统计学意义。Objective To detect serum levels of intereukin - 10（ IL - 10） in patients with vitiligo before and after treatment and to investigate its clinical significance. Methods ELISA method was used to detected the IL - 10 levels in 52 patients with vitiligo before and after treatment. Results Serum IL - 10 in vitiligo patients before treatment were significantly lower than those of healthy people （t = 7.80, P 〈 0.05 ）. After treatment, Serum levels of IL - 10 in vitiligo patients were significantly higher than that of the vitiligo patients before treatment （t = - 10. 76,P 〈 0.05 ）. Conclusion Serum IL - 10 in vitiligo patients after treatment are significantly higher than that of the vitiligo patients before treatment.

关 键 词：白癜风 白介素10 治疗 

分 类 号：R758.41[医药卫生—皮肤病学与性病学]