空洞检测算法自动化检测肺结节内空泡和空洞的可行性  

Feasibility of automatic detection of cavity and vacuole in pulmonary nodules using cavity detection algorithm

作　　者：王秋萍[1] 冯筠[2] 强永乾[1] 于楠[1] 邓蕾[1] 郭佑民[1] 

机构地区：[1]西安交通大学第一附属医院放射科,陕西西安710061 [2]西北大学信息科学与技术学院,陕西西安710127

出　　处：《中国医学影像技术》2014年第9期1309-1313,共5页Chinese Journal of Medical Imaging Technology

基　　金：卫生部行业专项资助项目(201402013);陕西省科技计划攻关项目(2011K12-05-08);陕西省科技统筹创新工程计划项目(2012KTCL03-07)

摘　　要：目的探讨利用空洞检测算法自动化检测肺结节内空泡和空洞的可行性。方法收集经病理或随访证实的49例肺结节,其中良性16例,恶性33例,所有患者均接受胸部CT检查。由2名高年资影像科医师盲法对CT图像进行主观评价,得出有无空泡和空洞的结论。利用基于阈值的空洞检测算法对CT图像中指定的肺结节进行有无空泡和空洞的客观评价。对两种评价方法所得结果进行对比分析。结果利用空洞检测算法对肺结节内空泡和空洞征象前后2次提取的数据稳定(Kappa=1),与高年资医师主观判读结果差异无统计学意义(χ2=0.862,P=0.353),且一致性较好(Kappa=0.785),并可明显节约每个结节数据提取时间[(7.72s±2.26)s vs(24.48±8.24)s,t=14.64,P<0.001]。结论利用空洞检测算法提取肺结节内空洞和空泡征象稳定、快捷,有望成为低年资医师诊断肺结节的辅助检测工具。Objective To assess the feasibility of automatic detecting cavity and vacuole in pulmonary nodules using cavitydetection algorithm. Methods Totally 49 patients with pulmonary nodules confirmed by pathology or clinical follow-upwere enrolled. There were 16 cases of benign nodule and 33 cases of malignant nodule. All cases underwent chest CT ex-aminations. CT image data were subjective judgment by two senior radiologists using double-blind method to determinewhether there was any cavitation and vacuole in pulmonary nodules. Meanwhile, the cavity and vacuole in specified pulmo-nary nodule on CT image were estimated using cavity detection algorithm based on threshold. The results produced fromthe two evaluatiing methods were compared. Results There was high consistency of cavity detection algorithm results be-tween two time measures （Kappa= 1）. No statistical difference was found between results obtained by cavity detection al-gorithm and subjective judgment. And there was good consistency （Kappa= O. 785）. The detecting time per nodule of cav-ity detection algorithm （[7.72±2.26]s） was shorter than that of subjective judgment （[24.48±8.24]s, t= 14.64, P〈0. 001）. Conclusion Cavity detection algorithm may become an auxiliary tool for resident doctors to detect cavity and vacu-ole in pulmonary nodules with advantages of stable and convenient.

关 键 词：肺 结节 空泡 空洞 体层摄影术 X线计算机 图像处理 计算机辅助 

分 类 号：R563[医药卫生—呼吸系统]