健脾化湿法治疗儿童特应性皮炎30例  

Treating 30 Cases of Atopic Dermatitis in Children by the Method of Invigorating Spleen to Eliminate Dampness

作　　者：周爱妍[1] 姬爱华[1] 史传奎[1] 高蕾[1] 

机构地区：[1]山东大学齐鲁儿童医院皮肤科,山东济南250022

出　　处：《西部中医药》2014年第8期73-74,共2页Western Journal of Traditional Chinese Medicine

摘　　要：目的:观察健脾化湿法治疗儿童特应性皮炎(atopic dermatitis,AD)的临床疗效及对血清总免疫球蛋白(TIgE)和嗜酸性粒细胞(EOS)的影响。方法:将60例AD患者按随机数字表法分为治疗组和对照组各30例。治疗组服用健脾化湿中药,对照组口服氯雷他定糖浆。分别于治疗前及治疗4周后记录SCORAD积分,检测2组患者TIgE水平和EOS计数。结果:总有效率治疗组为90.0%,对照组为66.3%,2组比较差异显著(P<0.05)。SCORAD评分及IgE和EOS治疗4周后2组均明显降低(P<0.05),治疗组降低更明显(P<0.05)。结论:健脾化湿法能显著改善AD患儿的皮损面积和严重程度,降低血清TIgE和EOS,疗效显著,不良反应小。Objective：To explore curative effects of the method of invigorating spleen to eliminate dampness in treating children with atopic dermatitis, its influence on serum total immunoglobulin E （TIgE） and eosinophile granulocyte （EOS）. Methods： Sixty AD patients were allocated to the treatment group and the control group according to random number table. The treatment group took the herbs of invigorating spleen and eliminating dampness orally, and the control group loratadine syrup. SCORAD scales were recorded before treating and after treating in four weeks, the level of TIgE and EOS of both groups were detected. Results：Total effective rate of the treatment group was 90.0%, higher than 66.3%of the control group with significant difference （P〈0.05）. SCORAD scales, the levels of IgE and EOS were decreased evidently after treating in four weeks （P〈0.05）, the decrease of the treatment group was more notable （P〈0.05）. Conclusion：The method of invigorating spleen to eliminate dampness could obviously improve lesion areas and the severity, lower the levels of TIgE and EOS, the method is effective and with minor adverse reaction.

关 键 词：皮炎 特应性 健脾化湿法 总免疫球蛋白 嗜酸性粒细胞 儿童 

分 类 号：R758.2[医药卫生—皮肤病学与性病学]